The natural extracellular matrix (ECM), thanks to its specific properties (eg, collagenous
lattice, a reservoir of growth factors, ECM‐cell anchoring areas, an optimal pH and CO2) …

The advancement and improvement in decellularization methods can be attributed to the
increasing demand for tissues and organs for transplantation. Decellularized tissues and …

Decellularization is the process of removal of native cells from tissue, leaving behind a three-
dimensional (3D) ultrastructure of extracellular matrix (ECM) proteins while preserving the …

Purpose. To establish an optimized and standardized protocol for the development of
optimal scaffold for bioengineering corneal substitutes, we used femtosecond laser to …

Trauma or infections associated critical bone defects lead to a huge economic burden in the
healthcare system worldwide. Recent advances in tissue engineering have led to potential …

Decellularized xenogeneic heart valves (DHVs) are promising products for valve
replacement. However, the widespread clinical application of such products is limited due to …

Abstract Annually, over 50,000 deaths are attributed to heart valve disease (HVD) in the
United States. The most common treatment for HVD, such as stenosis and regurgitation, is …

The main components used for tissue engineering are living cells, a scaffolding system
based on biomaterials, bioactive factors, and appropriate microenvironments that facilitate …

Tissue engineering uniquely applies concepts and techniques from biology and engineering
in order to heal or produce new tissues after disease or traumatic injury. A successful tissue …

Organ and tissue decellularization has been widely explored as a strategy to produce
extracellular matrix (ECM) biologic scaffolds for tissue engineering. Currently, different types …