Combination therapy for ischemic stroke: Novel approaches to lengthen therapeutic window of tissue plasminogen activator
T Knecht, C Borlongan, I dela Peña - Brain circulation, 2018 - journals.lww.com
Tissue plasminogen activator (tPA) thrombolysis continues to be the gold standard therapy
for ischemic stroke. Due to the time-limited treatment window, within 4.5 h of stroke onset …
for ischemic stroke. Due to the time-limited treatment window, within 4.5 h of stroke onset …
Review of bioactive secondary metabolites from marine bryozoans in the progress of new drugs discovery
XR Tian, HF Tang, XL Tian, JJ Hu… - Future medicinal …, 2018 - Taylor & Francis
Marine bryozoans play an important role for the discovery of novel bioactive compounds
among marine organisms. In this review, we summarize 164 new secondary metabolites …
among marine organisms. In this review, we summarize 164 new secondary metabolites …
Ursolic Acid Ameliorates Inflammation in Cerebral Ischemia and Reperfusion Injury Possibly via High Mobility Group Box 1/Toll-Like Receptor 4/NFκB Pathway
Y Wang, L Li, S Deng, F Liu, Z He - Frontiers in neurology, 2018 - frontiersin.org
Toll-like receptors (TLRs) play key roles in cerebral ischemia and reperfusion injury by
inducing the production of inflammatory mediators, such as interleukins (ILs) and tumor …
inducing the production of inflammatory mediators, such as interleukins (ILs) and tumor …
Selective role of Na+/H+ exchanger in Cx3cr1+ microglial activation, white matter demyelination, and post‐stroke function recovery
S Song, S Wang, VM Pigott, T Jiang, LM Foley… - Glia, 2018 - Wiley Online Library
Abstract Na+/H+ exchanger (NHE1) activation is required for multiple microglial functions.
We investigated effects of selective deletion of microglial Nhe1 in Cx3cr1‐CreER; Nhe1f/f …
We investigated effects of selective deletion of microglial Nhe1 in Cx3cr1‐CreER; Nhe1f/f …
Inhibition of inflammation, suppression of matrix metalloproteinases, induction of neurogenesis, and antioxidant property make bryostatin-1 a therapeutic choice for …
Multiple sclerosis (MS) is a neurodegenerative disease characterized by inflammation and
myelin damage. Pro-inflammatory cytokines, oxidative stress, high level of matrix …
myelin damage. Pro-inflammatory cytokines, oxidative stress, high level of matrix …
[PDF][PDF] Marine derived bioactive compounds for treatment of Alzheimer's disease
S Lakshmi, P Prakash, MM Essa… - Front Biosci (Elite …, 2018 - article.imrpress.com
Alzheimer's disease (AD) is mounting as social and economic encumbrance which are
accompanied by deficits in cognition and memory. Over the past decades, Alzheimer's …
accompanied by deficits in cognition and memory. Over the past decades, Alzheimer's …
[PDF][PDF] 延长溶栓时间窗在缺血性脑卒中tPA 治疗的临床前研究进展
陶依然， 刘婷婷， 孙芳玲， 艾厚喜， 郭德玉… - 中国比较医学 …, 2018 - zgbjyx.cnjournals.com
延长溶栓时间窗在缺血性脑卒中tPA治疗的临床前研究进展 Page 1 2018 年8 月 第28 卷第8 期
中国比较医学杂志 CHINESE JOURNAL OF COMPARATIVE MEDICINE August,2018 Vol. 28 …
中国比较医学杂志 CHINESE JOURNAL OF COMPARATIVE MEDICINE August,2018 Vol. 28 …
PKC activators and anticoagulant in regimen for treating stroke
DL Alkon - US Patent 9,889,183, 2018 - Google Patents
The present disclosure provides a method for treating stroke by administering to a subject an
anticoagulant, eg, recom binant tissue plasminogen activator (rTPA), and a protein kinase C …
anticoagulant, eg, recom binant tissue plasminogen activator (rTPA), and a protein kinase C …