Trans-envelope multidrug efflux pumps of Gram-negative bacteria and their synergism with the outer membrane barrier

HI Zgurskaya, VV Rybenkov, G Krishnamoorthy… - Research in …, 2018 - Elsevier
Antibiotic resistance is a serious threat to public health. Significant efforts are currently
directed toward containment of the spread of resistance, finding new therapeutic options …

[HTML][HTML] Role of the multidrug resistance efflux pump MexCD-OprJ in the Pseudomonas aeruginosa quorum sensing response

M Alcalde-Rico, J Olivares-Pacheco… - Frontiers in …, 2018 - frontiersin.org
Multidrug efflux pumps constitute a category of antibiotic resistance determinants that are a
part of the core bacterial genomes. Given their conservation, it is conceivable that they …

ATP-Binding Cassette Transporter VcaM from Vibrio cholerae is Dependent on the Outer Membrane Factor Family for Its Function

WJ Lu, HJ Lin, TK Janganan, CY Li, WC Chin… - International Journal of …, 2018 - mdpi.com
Vibrio cholerae ATP-binding cassette transporter VcaM (V. cholerae ABC multidrug
resistance pump) has previously been shown to confer resistance to a variety of medically …

Efflux pump-mediated quorum sensing: New avenues for modulation of antimicrobial resistance and bacterial virulence

M Lekshmi, A Parvathi, S Kumar, MF Varela - … Applications of Quorum …, 2018 - Springer
Bacterial pathogenesis is frequently enhanced by virulence mechanisms that facilitate
growth. Such virulence factors include biofilm formation and antimicrobial resistance …

Correlation between resistance of Pseudomonas aeruginosa to benzalkonium chloride and expression of efflux pump genes

MES Osman, HH El-Hendawy… - Journal of Applied …, 2018 - japsonline.com
Study of cross-resistance to other antimicrobial agents and efflux pump (EP) resistance
mechanism in benzalkonium chloride (BC) adapted Pseudomonas aeruginosa isolates …

Phenotypic and genotypic characterization of a novel multi-antibiotic-resistant, alginate hyperproducing strain of Pseudomonas mandelii isolated in Antarctica

S Higuera-Llantén, F Vásquez-Ponce… - Polar Biology, 2018 - Springer
Until recently, it was thought that Antarctica was a sterile continent due to extreme
environmental conditions. In fact, this cold continent is one of the most diverse in terms of …

Native CRISPR-Cas mediated in situ genome editing reveals extensive resistance synergy in the clinical multidrug resistant Pseudomonas aeruginosa

Z Xu, M Li, Y Li, H Cao, H Xiang, A Yan - bioRxiv, 2018 - biorxiv.org
Antimicrobial resistance (AMR) is imposing a global public health threat. Despite its
importance, characterizing drug resistance directly in the clinical isolates of resistant …

The multidrug resistance efflux pump MexCD-OprJ is a switcher of the Pseudomonas aeruginosa quorum sensing response

M Alcalde-Rico, J Olivares-Pacheco, C Alvarez-Ortega… - bioRxiv, 2018 - biorxiv.org
Most antibiotic resistance genes acquired by human pathogens originate from
environmental microorganisms. Therefore, understanding the additional functions of these …

Exposure to Plant Extract Causes the Variation of Antibiotic Susceptibility of Two Bacterial Strains (Salmonella Serotype Typhi and Staphylococcus aureus)

FE Mengo, SC Tchonang… - … of Advances in …, 2018 - article.researchpromo.com
Introduction: Several authors have associated the development of antibiotic resistance to the
use of antibiotics. But this development of resistance could also be associated with plant …

Native CRISPR-Cas mediated in situ genome editing reveals the exquisite interplay of resistance mutations in clinical multidrug resistant Pseudomonas aeruginosa

Z Xu, M Li, Y Li, H Cao, PC Woo, H Xiang, A Yan - 2018 - europepmc.org
Antimicrobial resistance (AMR) is imposing a global public health threat. Despite its
importance, resistance characterization in the native background of clinically isolated …