HLA-G mediated immune regulation is impaired by a single amino acid exchange in the alpha 2 domain
AA Celik, GS Simper, T Huyton, R Blasczyk… - Human Immunology, 2018 - Elsevier
The trade-off from HLA class I expression to HLA-G expression support the immune evasion
of malignant cells. The essential role of the virtually invariant HLA-G in immune tolerance …
of malignant cells. The essential role of the virtually invariant HLA-G in immune tolerance …
HLA-G peptide preferences change in transformed cells: Impact on the binding motif
AA Celik, GS Simper, W Hiemisch, R Blasczyk… - Immunogenetics, 2018 - Springer
HLA-G is known for its strictly restricted tissue distribution. HLA-G expression could be
detected in immune privileged organs and many tumor entities such as leukemia, multiple …
detected in immune privileged organs and many tumor entities such as leukemia, multiple …
[PDF][PDF] Cytomegalovirus gp40/m152 uses TMED10 as ER anchor to retain MHC class I
The murine cytomegalovirus immunoevasin m152/gp40 binds major histocompatibility
complex (MHC) class I molecules and retains them in the early secretory pathway by a …
complex (MHC) class I molecules and retains them in the early secretory pathway by a …
HLA-F on HLA-null 721.221 cells activates primary NK cells expressing the activating killer Ig-like receptor KIR3DS1
Z Kiani, FP Dupuy, J Bruneau, B Lebouché… - The Journal of …, 2018 - journals.aai.org
NK cells elicit important responses against transformed and virally infected cells. Carriage of
the gene encoding the activating killer Ig-like receptor KIR3DS1 is associated with slower …
the gene encoding the activating killer Ig-like receptor KIR3DS1 is associated with slower …
The immunopeptidomic landscape of clear cell renal cell carcinoma: identification and characterization of T-cell epitopes for immunotherapeutic approaches
M Di Marco - 2018 - tobias-lib.ub.uni-tuebingen.de
Current therapy of ccRCC is commonly constrained by low response rates and frequent
resistance against administered drugs. In recent years, drug discovery is focusing on the …
resistance against administered drugs. In recent years, drug discovery is focusing on the …
[PDF][PDF] The basis of HLA-G mediated dysregulation of immune effector cells
A Celik - 2018 - scholar.archive.org
The major histocompatibility complex (MHC) was first described as the genomic region that
is responsible for the rejection of transplanted tissue grafts between different strains of mice …
is responsible for the rejection of transplanted tissue grafts between different strains of mice …