The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

It has become increasingly evident in recent years that the gut microbiome and the brain
communicate in a bidirectional manner, with each possibly affecting the other's functions …

Previous studies suggest that gut microbiota is associated with neuropsychiatric disorders,
such as Parkinson's disease, amyotrophic lateral sclerosis, and depression. However …

Inflammasome signalling is an emerging pillar of innate immunity and has a central role in
the regulation of gastrointestinal health and disease. Activation of the inflammasome …

Activation of microglia and expression of the inflammatory cytokine interleukin-1 (IL-1) in the
CNS have become almost synonymous with neuroinflammation. In numerous studies …

Depression is one of the foremost psychological illness which is closely leagued with
inflammation. Crocin is a natural product that exhibits both anti-inflammatory and anti …

We propose the “microbiota‐inflammasome” hypothesis of major depressive disorder (MDD,
a mental illness affecting the way a person feels and thinks, characterized by long‐lasting …

Humans have over 100 trillion bacteria, highly abundant in the intestinal tract. Evidence
suggests that intestinal microbiota is associated with the neuro-endocrine-immune pathways …

Backgrounds Although increasing evidence suggests a role for the gut microbiota in
neurodevelopment, the actual structure and composition of microbiota in children with …

Irritable bowel syndrome (IBS) is one of the most common of all medical disorders worldwide
and, while for some it represents no more than a nuisance, for others it imposes significant …