The functions and unique features of long intergenic non-coding RNA

JD Ransohoff, Y Wei, PA Khavari - Nature reviews Molecular cell …, 2018 - nature.com
Long intergenic non-coding RNA (lincRNA) genes have diverse features that distinguish
them from mRNA-encoding genes and exercise functions such as remodelling chromatin …

Noncoding RNA s in disease

E Lekka, J Hall - FEBS letters, 2018 - Wiley Online Library
Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …

Noncoding RNAs: master regulators of inflammatory signaling

CL Chew, SA Conos, B Unal, V Tergaonkar - Trends in molecular medicine, 2018 - cell.com
Inflammatory signaling underlies many diseases, from arthritis to cancer. Our understanding
of inflammation has thus far been limited to the world of proteins, because we are only just …

Extracellular vesicles and their nucleic acids for biomarker discovery

F Momen-Heravi, SJ Getting, SA Moschos - Pharmacology & therapeutics, 2018 - Elsevier
Extracellular vesicles (EVs) are a heterogenous population of vesicles originate from cells.
EVs are found in different biofluids and carry different macromolecules, including proteins …

Translation of neutrally evolving peptides provides a basis for de novo gene evolution

J Ruiz-Orera, P Verdaguer-Grau… - Nature ecology & …, 2018 - nature.com
Accumulating evidence indicates that some protein-coding genes have originated de novo
from previously non-coding genomic sequences. However, the processes underlying de …

SmProt: a database of small proteins encoded by annotated coding and non-coding RNA loci

Y Hao, L Zhang, Y Niu, T Cai, J Luo, S He… - Briefings in …, 2018 - academic.oup.com
Small proteins is the general term for proteins with length shorter than 100 amino acids.
Identification and functional studies of small proteins have advanced rapidly in recent years …

The state of long non-coding RNA biology

JS Mattick - Non-coding RNA, 2018 - mdpi.com
Transcriptomic studies have demonstrated that the vast majority of the genomes of mammals
and other complex organisms is expressed in highly dynamic and cell-specific patterns to …

Long non‐coding RNA CASC 15 regulates gastric cancer cell proliferation, migration and epithelial mesenchymal transition by targeting CDKN 1A and ZEB 1

Q Wu, S Xiang, J Ma, P Hui, T Wang… - Molecular …, 2018 - Wiley Online Library
Long non‐coding RNA (lnc RNA) is responsible for a diverse range of cellular functions,
such as transcriptional and translational regulation and variance in gene expression. The …

The role of long noncoding RNAs in central nervous system and neurodegenerative diseases

CW Wei, T Luo, SS Zou, AS Wu - Frontiers in behavioral neuroscience, 2018 - frontiersin.org
Long noncoding RNAs (lncRNAs) refer to a group of noncoding RNAs (ncRNAs) that has a
transcript of more than 200 nucleotides in length in eukaryotic cells. The lncRNAs regulate …

Interactions between short and long noncoding RNAs

I Ulitsky - FEBS letters, 2018 - Wiley Online Library
It is now evident that noncoding RNAs play key roles in regulatory networks determining cell
fate and behavior, in a myriad of different conditions, and across all species. Among these …