Pathogenesis of progressive multifocal leukoencephalopathy and risks associated with treatments for multiple sclerosis: a decade of lessons learned
EO Major, TA Yousry, DB Clifford - The Lancet Neurology, 2018 - thelancet.com
Progressive multifocal leukoencephalopathy (PML) is a rare, devastating demyelinating
disease of the CNS caused by the JC virus (JCV) that occurs in patients with compromised …
disease of the CNS caused by the JC virus (JCV) that occurs in patients with compromised …
[PDF][PDF] John Cunningham virus: an overview on biology and disease of the etiological agent of the progressive multifocal leukoencephalopathy
V Pietropaolo, C Prezioso, F Bagnato… - New …, 2018 - newmicrobiologica.org
JCV is a small (∼ 45 nm), non-enveloped, circular, double-stranded DNA genome,
arranged in 72 viral capsomeres with icosahedral symmetry (Tan et al., 2009a). The genome …
arranged in 72 viral capsomeres with icosahedral symmetry (Tan et al., 2009a). The genome …
[HTML][HTML] T cell deficiencies as a common risk factor for drug associated progressive multifocal leukoencephalopathy
D Pavlovic, MA Patel, AC Patera, I Peterson… - Immunobiology, 2018 - Elsevier
Progressive multifocal leukoencephalopathy (PML) is a disease of the central nervous
system caused by neuropathogenic prototypes of ubiquitous community-acquired JC virus …
system caused by neuropathogenic prototypes of ubiquitous community-acquired JC virus …
[HTML][HTML] Exploring the role of NCCR variation on JC polyomavirus expression from dual reporter minicircles
AS L'Honneur, H Leh, F Laurent-Tchenio, U Hazan… - PLoS …, 2018 - journals.plos.org
JC virus (JCV), a ubiquitous human polyomavirus, can cause fatal progressive multifocal
leukoencephalopathy (PML) in immune compromised patients. The viral genome is …
leukoencephalopathy (PML) in immune compromised patients. The viral genome is …
[HTML][HTML] 进行性多灶性脑白质病的发病机制研究进展
HU Caiqin, ZHU Biao - Journal of Zhejiang University (Medical …, 2018 - ncbi.nlm.nih.gov
进行性多灶性脑白质病（ PML） 是由JC 多瘤病毒（ JCV） 引起的一种罕见、
致命的中枢神经脱髓鞘疾病， 主要发生在免疫系统受损的患者中。 JCV 的致病变异在PML …
致命的中枢神经脱髓鞘疾病， 主要发生在免疫系统受损的患者中。 JCV 的致病变异在PML …
[PDF][PDF] Crossing Barriers: How JC Virus Crosses the Blood Brain Barrier and Induces Progressive Multifocal Leukoencephalopathy in Patients on Disease-Modifying …
ME Baeva - JEMI PEARLS, 2018 - jemi.microbiology.ubc.ca
Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease caused
by the John Cunningham virus (JCV). While it is known to cause lytic infection in …
by the John Cunningham virus (JCV). While it is known to cause lytic infection in …
Viral and Host Factor Interactions in the Regulation of JC Virus Reactivation
MJ Craigie - 2018 - scholarshare.temple.edu
JC virus (JCV) is a human neurotropic polyomavirus and the etiologic agent of progressive
multifocal leukoencephalopathy (PML), a demyelinating disease of the white matter. PML is …
multifocal leukoencephalopathy (PML), a demyelinating disease of the white matter. PML is …