Unraveling the role of angiogenesis in cancer ecosystems
I Zuazo-Gaztelu, O Casanovas - Frontiers in Oncology, 2018 - frontiersin.org
Activation of the tumor and stromal cell-driven angiogenic program is one of the first
requirements in the tumor ecosystem for growth and dissemination. The understanding of …
requirements in the tumor ecosystem for growth and dissemination. The understanding of …
Biomechanical characterization at the cell scale: present and prospects
The rapidly growing field of mechanobiology demands for robust and reproducible
characterization of cell mechanical properties. Recent achievements in understanding the …
characterization of cell mechanical properties. Recent achievements in understanding the …
Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation
The mechanical properties of extracellular matrices can control the function of cells. Studies
of cellular responses to biomimetic soft materials have been largely restricted to hydrogels …
of cellular responses to biomimetic soft materials have been largely restricted to hydrogels …
Bimodal sensing of guidance cues in mechanically distinct microenvironments
ED Tabdanov, VV Puram, Z Win, A Alamgir… - Nature …, 2018 - nature.com
Contact guidance due to extracellular matrix architecture is a key regulator of carcinoma
invasion and metastasis, yet our understanding of how cells sense guidance cues is limited …
invasion and metastasis, yet our understanding of how cells sense guidance cues is limited …
Mechanisms linking mechanotransduction and cell metabolism
AM Salvi, KA DeMali - Current opinion in cell biology, 2018 - Elsevier
Throughout their lifetimes, all cells experience force. These forces are sensed by cell surface
adhesion receptors, such as the cadherins and integrins. Much attention has focused on …
adhesion receptors, such as the cadherins and integrins. Much attention has focused on …
Mechanoelectrical transduction in chondrocytes
MR Servin‐Vences, J Richardson… - Clinical and …, 2018 - Wiley Online Library
Cartilage tissue lines the joints of mammals, helping to lubricate joint movement and
distribute mechanical loads. This tissue is comprised of isolated cells known as …
distribute mechanical loads. This tissue is comprised of isolated cells known as …
Mechanotargeting: Mechanics‐Dependent Cellular Uptake of Nanoparticles
Targeted delivery of nanoparticle (NP)‐based diagnostic and therapeutic agents to
malignant cells and tissues has exclusively relied on chemotargeting, wherein NPs are …
malignant cells and tissues has exclusively relied on chemotargeting, wherein NPs are …
Vascular smooth muscle cells direct extracellular dysregulation in aortic stiffening of hypertensive rats
TT Hays, B Ma, N Zhou, S Stoll, WJ Pearce, H Qiu - Aging cell, 2018 - Wiley Online Library
Aortic stiffening is an independent risk factor that underlies cardiovascular morbidity in the
elderly. We have previously shown that intrinsic mechanical properties of vascular smooth …
elderly. We have previously shown that intrinsic mechanical properties of vascular smooth …
Protein–substrate adhesion in microcontact printing regulates cell behavior
Microcontact printing (μCP) is widely used to create patterns of biomolecules essential for
studies of cell mechanics, migration, and tissue engineering. However, different types of …
studies of cell mechanics, migration, and tissue engineering. However, different types of …
Nonlinear cellular mechanical behavior adaptation to substrate mechanics identified by atomic force microscope
Cell–substrate interaction plays an important role in intracellular behavior and function.
Adherent cell mechanics is directly regulated by the substrate mechanics. However …
Adherent cell mechanics is directly regulated by the substrate mechanics. However …