The identification of the mutation causing Huntington's disease (HD) has led to the
generation of a large number of mouse models. These models are used to further enhance …

Transgenic mouse models of Huntington's disease (HD), a neurodegenerative condition
caused by a single gene mutation, have been transformative in their ability to reveal the …

Huntington disease (HD) is a neurodegenerative disorder caused by an expanded CAG
repeat in the Huntington disease gene. The symptomatic stage of the disease is defined by …

GABA is a widely distributed inhibitory neurotransmitter. GABA-A receptors are hetero-
pentameric channels assembled in multiple combinations from 19 available subunits; this …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by
a trinucleotide expansion in the HD gene, resulting in an extended polyglutamine tract in the …

Abstract γ-Aminobutyric acid (GABA), plays a key role in all stages of life, also is considered
the main inhibitory neurotransmitter. GABA activates two kind of membrane receptors known …

Huntington's disease (HD) is caused by an expansion of CAG repeats in the HTT gene,
leading to expression of mutant huntingtin (mHTT) and selective striatal neuronal loss …

Background: The threshold of CAG repeat expansion in the HTT gene that causes HD is 36
CAG repeats, although 'superlong'expansions are found in individual neurons in post …

γ-Aminobutyric acid (GABA), plays a key role in all stages of life, also is considered the main
inhibitory neurotransmitter. GABA activates two kind of membrane receptors known as …

The threshold of CAG repeat expansion in the HTT gene that causes HD is 36 CAG repeats,
although 'superlong'expansions are found in individual neurons in post mortem brains …