The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Oxytocin and rodent models of addiction

KC Leong, S Cox, C King, H Becker… - International review of …, 2018 - Elsevier
Interest for the use of oxytocin as a treatment for addiction began over 40 years ago. Better
known for its roles in parturition, lactation and pair bonding, oxytocin also has anxiolytic …

A systematic review and quantitative meta‐analysis of the effects of oxytocin on feeding

M Leslie, P Silva, Y Paloyelis, J Blevins… - Journal of …, 2018 - Wiley Online Library
The anorexigenic effects of oxytocin have been widely documented and accepted; however,
no study has yet used the Preferred Reporting Items for Systematic Reviews and Meta …

Environmental enrichment enhances conditioned place preference to ethanol via an oxytocinergic-dependent mechanism in male mice

M Rae, P Zanos, P Georgiou, P Chivers, A Bailey… - …, 2018 - Elsevier
Environmental conditions, such as stress and environmental enrichment (EE), influence
predisposition to alcohol use/abuse; however, the underlying mechanisms remain unknown …

Regionally specific effects of oxytocin on reinstatement of cocaine seeking in male and female rats

RA Weber, CN Logan, KC Leong, J Peris… - International Journal …, 2018 - academic.oup.com
Background Oxytocin reduces cued reinstatement of cocaine seeking in male and female
rats, but the underlying neurobiology has not been uncovered. The majority of effort on this …

The role of the vasopressin V1A receptor in oxytocin modulation of methamphetamine primed reinstatement

NA Everett, IS McGregor, SJ Baracz, JL Cornish - Neuropharmacology, 2018 - Elsevier
The neuropeptide oxytocin has shown promise as an effective therapy in pre-clinical models
of methamphetamine (METH) addiction. The nucleus accumbens core (NAcc) has been …

Attenuated cocaine-seeking after oxytocin administration in male and female rats

AS Kohtz, B Lin, ME Smith, G Aston-Jones - Psychopharmacology, 2018 - Springer
Rationale Initial drug abstinence (modeled here as Extinction Day 1, ED1) is a critical time
point in the progression of addiction that is strongly influenced by stress and sex. ED1 …

The multidimensional therapeutic potential of targeting the brain oxytocin system for the treatment of substance use disorders

MT Bowen, ID Neumann - Behavioral Pharmacology of Neuropeptides …, 2018 - Springer
The neuropeptide oxytocin is released both into the blood and within the brain in response
to reproductive stimuli, such as birth, suckling and sex, but also in response to social …

Systemic Oxytocin Administration Alters Mesolimbic Dopamine Relase

MK Estes - 2018 - digitalcommons.memphis.edu
Growing research indicates oxytocin may be involved in relieving anxiety and attenuating
the rewarding effects of psychostimulants. The present study investigated the effects of …