[HTML][HTML] Pja2 inhibits Wnt/beta-catenin signaling by reducing the level of TCF/LEF1

Y Song, S Lee, JR Kim, E Jho - Int. J. Stem Cells, 2018 - synapse.koreamed.org
Ubiquitination of proteins plays an essential role in various cellular processes, including
protein degradation, DNA repair, and cell signaling pathways. Previous studies have shown …

Targeting the architecture of deregulated protein complexes in cancer

E Stefan, J Troppmair, K Bister - … in protein chemistry and structural biology, 2018 - Elsevier
The architectures of central signaling hubs are precisely organized by static and dynamic
protein–protein interactions (PPIs). Upon deregulation, these PPI platforms are capable to …