Enhancing solubility of poorly aqueous soluble drugs: Critical appraisal of techniques

D Singh, N Bedi, AK Tiwary - Journal of pharmaceutical investigation, 2018 - Springer
A wide variety of new medication disclosures launched by specific benefits of the general
public are laced with poor aqueous solubility problems that often obstruct their bioavailability …

Influence of lidocaine forms (salt vs. freebase) on properties of drug–eudragit® L100-55 extrudates prepared by reactive melt extrusion

X Liu, X Ma, E Kun, X Guo, Z Yu, F Zhang - International journal of …, 2018 - Elsevier
This study examines the preparation of sustained-release lidocaine polyelectrolyte complex
using reactive melt extrusion. Eudragit L100-55 was selected as the ionic polymer. The …