[HTML][HTML] Negative regulators of platelet activation and adhesion

L Stefanini, W Bergmeier - Journal of Thrombosis and Haemostasis, 2018 - Elsevier
Platelets are small anucleated cells that constantly patrol the cardiovascular system to
preserve its integrity and prevent excessive blood loss where the vessel lining is breached …

[HTML][HTML] Involvement of TIMP-1 in PECAM-1-mediated tumor dissemination

V Abraham, G Cao, A Parambath… - International …, 2018 - spandidos-publications.com
Platelet endothelial cell adhesion molecule‑1 (PECAM‑1) is expressed on the vascular
endothelium and has been implicated in the late progression of metastatic tumors. The …

Allicin improves the function of cardiac microvascular endothelial cells by increasing PECAM-1 in rats with cardiac hypertrophy

P Shi, Y Cao, J Gao, B Fu, J Ren, L Ba, C Song, H Qi… - Phytomedicine, 2018 - Elsevier
Objective Cardiac microvascular damage is significantly associated with the development of
cardiac hypertrophy (CH). Researchers found that allicin could inhibit CH, but the …

[HTML][HTML] Matrilysin/MMP-7 cleavage of perlecan/HSPG2 complexed with semaphorin 3A supports FAK-mediated stromal invasion by prostate cancer cells

BJ Grindel, JR Martinez, TV Tellman, DA Harrington… - Scientific reports, 2018 - nature.com
Interrupting the interplay between cancer cells and extracellular matrix (ECM) is a strategy to
halt tumor progression and stromal invasion. Perlecan/heparan sulfate proteoglycan 2 …

Glycosylation controls cooperative PECAM-VEGFR2-β3 integrin functions at the endothelial surface for tumor angiogenesis

R Imamaki, K Ogawa, Y Kizuka, Y Komi, S Kojima… - Oncogene, 2018 - nature.com
Most of the angiogenesis inhibitors clinically used in cancer treatment target the vascular
endothelial growth factor (VEGF)/VEGF receptor (VEGFR) pathway. However, the current …

CRISPR-mediated deletion of the PECAM-1 cytoplasmic domain increases receptor lateral mobility and strengthens endothelial cell junctional integrity

D Liao, H Mei, Y Hu, DK Newman, PJ Newman - Life sciences, 2018 - Elsevier
Aims PECAM-1 is an abundant endothelial cell surface receptor that becomes highly
enriched at endothelial cell-cell junctions, where it functions to mediate leukocyte …

[HTML][HTML] E-Cadherin, CD31 在大肠癌中的表达及意义

孙红梅, 武金宝 - Journal of Physiology Studies, 2018 - hanspub.org
大肠癌(Colorectal cancer, CRC) 是最常见的恶性肿瘤之一. 转移及浸润在大肠癌发生,
发展过程中起着重要的作用, E-cadherin, CD31 与大肠癌的转移, 浸润, 肿瘤分期 …

[HTML][HTML] Application of medical adhesive inhibits intimal hyperplasia involving the downregulation of ERK1/2 and eNOS levels

S Chai, Y Yu, H Li, M Gao, B Li… - Molecular Medicine …, 2018 - spandidos-publications.com
Vein graft remains the most broadly applied vascular material in coronary artery bypass
surgery. However, the restenosis rate of the vein bridge following angioplasty is high. The …

[引用][C] Expression and Significance of E-Cadherin and CD31 in Colorectal Cancer

H Sun, J Wu - 2018