Immunotherapy is among the most rapidly evolving treatment strategies in oncology. The
therapeutic potential of immune-checkpoint inhibitors is exemplified by the recent hail of …

Immunotherapy has emerged as a highly effective treatment for numerous cancers. Use of
checkpoint inhibitors against various molecules including programmed cell death protein‐1 …

Advances in immunotherapy utilizing immune checkpoint inhibitors (ICIs) have transformed
the treatment landscapes of several malignancies in recent years. Oncologists are now …

Purpose: Liver metastasis develops in> 50% of patients with colorectal cancer (CRC), and is
a leading cause of CRC-related mortality. We aimed to identify which inhibitory immune …

Background Tumor mutational burden (TMB) is an increasingly important biomarker for
immune checkpoint inhibitors. Recent publications have described strong association …

Aim We examined the programmed death-ligand 1 (PD-L1) expression in surgically
resected pancreatic adenosquamous carcinoma (PASC) samples. Furthermore, the …

Nucleic acid vaccines have attracted enormous attention for resolving the limitations of
conventional vaccines using live attenuated viruses. Because nucleic acid vaccines can be …

Cancers of the gastrointestinal tract have limited available treatments and are often
associated with a poor prognosis. Clinical trials and translational work associated with these …

Detection analysis of microsatellite instability status for the diagnosis and therapy of Lynch
syndrome-related cancers. Lynch syndrome (LS) is an autosomal dominant genetic disorder …

Purpose: Liver metastasis develops in> 50% of patients with colorectal cancer (CRC), and is
a leading cause of CRC-related mortality. We aimed to identify which inhibitory immune …