Mechanisms of physiological and pathological cardiac hypertrophy

M Nakamura, J Sadoshima - Nature Reviews Cardiology, 2018 - nature.com
Cardiomyocytes exit the cell cycle and become terminally differentiated soon after birth.
Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual …

Sex-specific physiology and cardiovascular disease

CL Shufelt, C Pacheco, MS Tweet, VM Miller - Sex-Specific Analysis of …, 2018 - Springer
Sex differences in cardiovascular diseases can be classified as those which are specific to
one sex and those that differ in incidence, prevalence, etiology, symptomatology, response …

2018 ESC guidelines for the management of cardiovascular diseases during pregnancy: the task force for the management of cardiovascular diseases during …

V Regitz-Zagrosek, JW Roos-Hesselink… - European heart …, 2018 - academic.oup.com
not override in any way whatsoever the individual responsibility of health professionals to
make appropriate and accurate decisions in consideration of each patient's health condition …

Cardiotoxicity with vascular endothelial growth factor inhibitor therapy

RM Touyz, J Herrmann - NPJ Precision Oncology, 2018 - nature.com
Angiogenesis inhibitors targeting the vascular endothelial growth factor (VEGF) signaling
pathway (VSP) have been important additions in the therapy of various cancers, especially …

PGC1α in the kidney

MR Lynch, MT Tran, SM Parikh - American Journal of …, 2018 - journals.physiology.org
Acute kidney injury (AKI) arising from diverse etiologies is characterized by mitochondrial
dysfunction. The peroxisome proliferator-activated receptor γ coactivator-1alpha (PGC1α), a …

Peripartum cardiomyopathy: an update

F Azibani, K Sliwa - Current heart failure reports, 2018 - Springer
Abstract Purpose of Review Peripartum cardiomyopathy (PPCM) is an idiopathic disorder
defined as heart failure occurring in women during the last month of pregnancy and up to 5 …

Gene-Centric Analysis of Preeclampsia Identifies Maternal Association at PLEKHG1

KJ Gray, VP Kovacheva, H Mirzakhani, AC Bjonnes… - …, 2018 - Am Heart Assoc
The genetic susceptibility to preeclampsia, a pregnancy-specific complication with
significant maternal and fetal morbidity, has been poorly characterized. To identify maternal …

Incidence, risk factors, and clinical characteristics of peripartum cardiomyopathy in South Korea

S Lee, GJ Cho, GU Park, LY Kim, TS Lee… - Circulation: Heart …, 2018 - Am Heart Assoc
Background: Peripartum cardiomyopathy (PPCM) is a rare disorder associated with
pregnancy that can lead to life-threatening conditions. The incidence and clinical …

Long‐term cardiac function after peripartum cardiomyopathy and preeclampsia: a Danish nationwide, clinical follow‐up study using maximal exercise testing and …

AS Ersbøll, AS Bojer, MG Hauge… - Journal of the …, 2018 - Am Heart Assoc
Background Long‐term clinical studies of peripartum cardiomyopathy (PPCM) are few. We
aimed to measure the long‐term effect of PPCM on cardiac function in comparison with the …

Important signals regulating coronary artery angiogenesis

S Shoeibi, P Mozdziak, S Mohammadi - Microvascular research, 2018 - Elsevier
Angiogenesis is a complex process of budding, the formation of new blood vessels from pre-
existing microvessels, via migration, proliferation and survival. Vascular angiogenesis …