Cell migration is an adaptive process that depends on and responds to physical and
molecular triggers. Moving cells sense and respond to tissue mechanics and induce …

The worldwide shortage of organs fosters significant advancements in regenerative
therapies. Tissue engineering and regeneration aim to supply or repair organs or tissues by …

Current 3D printing of tissue is restricted by the use of biomaterials that do not recapitulate
the native properties of the extracellular matrix (ECM). These restrictions have thus far …

Physical features of the extracellular matrix (ECM) heavily influence cell migration strategies
and efficiency. Migration in and on fibrous ECMs is of significant physiologic importance, but …

Collagen hydrogels are widely used for in-vitro experiments and tissue engineering
applications. Their use has been extended due to their biocompatibility with cells and their …

Despite the various reported approaches to generate osteochondral composites by
combination of different cell types and materials, engineering of templates with the capacity …

Bone regeneration is strongly dependent on the capacity of cells to move in a 3D
microenvironment, where a large cascade of signals is activated. To improve the …

In engineering of tissue analogues, upscaling to clinically-relevant sized constructs remains
a significant challenge. The successful integration of a vascular network throughout the …

Osteoinductive biomaterials represent a promising approach to advance bone grafting.
Despite promising, the combination of sustained biodegradability, mechanical strength, and …

Three-dimensional (3D) cell culture systems have gained increasing interest not only for 3D
migration studies but also for their use in drug screening, tissue engineering, and ex vivo …