Nuclear long noncoding RNAs: key regulators of gene expression
A significant portion of the human genome encodes genes that transcribe long nonprotein-
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …
Non-coding RNAs in hepatocellular carcinoma: molecular functions and pathological implications
CM Wong, FHC Tsang, IOL Ng - Nature reviews Gastroenterology & …, 2018 - nature.com
Hepatocellular carcinoma (HCC) is a leading lethal malignancy worldwide. However, the
molecular mechanisms underlying liver carcinogenesis remain poorly understood. Over the …
molecular mechanisms underlying liver carcinogenesis remain poorly understood. Over the …
[HTML][HTML] Exploring the mechanisms behind long noncoding RNAs and cancer
MM Balas, AM Johnson - Non-coding RNA research, 2018 - Elsevier
Over the past decade, long noncoding RNAs (lncRNAs) have been identified as significant
players in gene regulation. They are often differentially expressed and widely-associated …
players in gene regulation. They are often differentially expressed and widely-associated …
[PDF][PDF] Taurine up‐regulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma
YH Lin, MH Wu, YH Huang, CT Yeh, ML Cheng… - …, 2018 - Wiley Online Library
Cancer cells display altered glucose metabolism characterized by a preference for aerobic
glycolysis. The aerobic glycolytic phenotype of hepatocellular carcinoma (HCC) is often …
glycolysis. The aerobic glycolytic phenotype of hepatocellular carcinoma (HCC) is often …
[HTML][HTML] LncRNA CDKN2BAS predicts poor prognosis in patients with hepatocellular carcinoma and promotes metastasis via the miR-153-5p/ARHGAP18 signaling …
J Chen, X Huang, W Wang, H Xie, J Li, Z Hu… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
Background: Growing evidence shows that long noncoding RNAs (lncRNAs) play a crucial
role in cancer progression. However, whether lncRNA CDKN2BAS is involved in human …
role in cancer progression. However, whether lncRNA CDKN2BAS is involved in human …
[HTML][HTML] LncRNA MALAT1 promotes cancer metastasis in osteosarcoma via activation of the PI3K-Akt signaling pathway
Y Chen, W Huang, W Sun, B Zheng, C Wang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: LncRNAs have been reported to be vital regulators of the progression of
osteosarcoma, although the underlying mechanisms are not completely understood …
osteosarcoma, although the underlying mechanisms are not completely understood …
[HTML][HTML] Long noncoding RNA TUG1 facilitates osteogenic differentiation of periodontal ligament stem cells via interacting with Lin28A
Q He, S Yang, X Gu, M Li, C Wang, F Wei - Cell Death & Disease, 2018 - nature.com
Periodontal ligament stem cells (PDLSCs) are mesenchymal stem cells derived from dental
tissues with multidirectional differentiation potential and excellent self-renewing ability …
tissues with multidirectional differentiation potential and excellent self-renewing ability …
[HTML][HTML] The role of long non-coding RNAs in hepatocarcinogenesis
M Lanzafame, G Bianco, LM Terracciano… - International journal of …, 2018 - mdpi.com
Whole-transcriptome analyses have revealed that a large proportion of the human genome
is transcribed in non-protein-coding transcripts, designated as long non-coding RNAs …
is transcribed in non-protein-coding transcripts, designated as long non-coding RNAs …
LncRNA TUG1 interacting with miR-144 contributes to proliferation, migration and tumorigenesis through activating the JAK2/STAT3 pathway in hepatocellular …
J Lv, Y Kong, Z Gao, Y Liu, P Zhu, Z Yu - The international journal of …, 2018 - Elsevier
Recently, it is reported that taurine upregulated gene 1 (TUG1) participates in the tumor
progression by acting as a competing endogenous RNA (ceRNA) of miRNAs. Nonetheless …
progression by acting as a competing endogenous RNA (ceRNA) of miRNAs. Nonetheless …
[HTML][HTML] Role of lncRNA and EZH2 interaction/regulatory network in lung cancer
M Su, Y Xiao, J Tang, J Wu, J Ma, B Tian, Y Zhou… - Journal of …, 2018 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of cancer-related deaths worldwide. Long non-coding
RNAs (lncRNAs) are non-protein-coding transcripts and longer than 200 nucleotides …
RNAs (lncRNAs) are non-protein-coding transcripts and longer than 200 nucleotides …