Nanocarriers in advanced drug targeting: setting novel paradigm in cancer therapeutics

MH Akhter, M Rizwanullah, J Ahmad… - Artificial cells …, 2018 - Taylor & Francis
Cancer has been growing nowadays consequently high number of death ascertained
worldwide. The medical intervention involves chemotherapy, radiation therapy and surgical …

Polysaccharide-based nanoparticles for gene delivery

MS Huh, EJ Lee, H Koo, JY Yhee, KS Oh, S Son… - Polymeric gene delivery …, 2018 - Springer
Nanoparticles based on nanotechnology and biotechnology have emerged as efficient
carriers for various biopharmaceutical agents including proteins and genes. In particular …

Synthesis and characterization of chitosan ascorbate nanoparticles for therapeutic inhibition for cervical cancer and their in silico modeling

V Sekar, K Rajendran, S Vallinayagam… - Journal of industrial and …, 2018 - Elsevier
This study focuses on synthesis and characterization of chitosan ascorbate nanoparticles
(CANs) from a salified carboxylate form of chitosan with ascorbic acid. Evident changes …

Increased endocytosis of magnetic nanoparticles into cancerous urothelial cells versus normal urothelial cells

J Lojk, VB Bregar, K Strojan, S Hudoklin… - Histochemistry and Cell …, 2018 - Springer
The blood–urine barrier is the tightest and most impermeable barrier in the body and as
such represents a problem for intravesical drug delivery applications. Differentiation …

Application of nanobioformulations for controlled release and targeted biodistribution of drugs

J Jampilek, K Král'ová - Nanobiomaterials, 2018 - taylorfrancis.com
This chapter focuses on natural-based biocompatible and biodegradable materials that are
used as matrices/carriers for controlled release or targeted biodistribution of nanoscale …

Ultra‐small Albumin Templated Gd/Ru Composite Nanodots for In Vivo Dual modal MR/Thermal Imaging Guided Photothermal Therapy

P Xu, H Wu, D Wang, G Zhao, F Li, B Qiu… - Advanced …, 2018 - Wiley Online Library
Multifunctional theranostic nanoagents which realize precise diagnosis and treatment of
tumors are attracting increasing interests in recent years. However, efficient and controlled …

Injectable visible light-cured glycol chitosan hydrogels with controlled release of anticancer drugs for local cancer therapy in vivo: a feasible study

H Hyun, MH Park, W Lim, SY Kim, D Jo… - Artificial Cells …, 2018 - Taylor & Francis
Currently available chemotherapy is associated with serious side effects, and therefore
novel drug delivery systems (DDSs) are required to specifically deliver anticancer drugs to …

Synthesis of Biotin-Modified Galactosylated Chitosan Nanoparticles and Their Characteristics in Vitro and in Vivo

M Cheng, D Ma, K Zhi, B Liu, W Zhu - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: Our previous study found that a nanoparticle drug delivery
system that operates as a drug carrier and controlled release system not only improves the …

Chitosan-based nano-biocomposites and their applications in medicine and pharmaceutics

Z Yang, P Li, A McDonagh, S Li, M Lv… - Current Organic …, 2018 - ingentaconnect.com
Background: Chitosan-based nano-biocomposite has received more and more attentions in
the past few years because of the outstanding merits that chitosan is a natural polymer with …

Chitosan-based self-assembled nanocarriers coordinated to cisplatin for cancer treatment

R Trummer, W Rangsimawong, W Sajomsang… - RSC …, 2018 - pubs.rsc.org
Polymeric nanocarriers were prepared via a dialysis method using three chitosan
derivatives, N-benzyl-N, O-succinyl chitosan (BSCT), N-naphthyl-N, O-succinyl chitosan …