Mental disorders and an acidic glycan-from the perspective of polysialic acid (PSA/polySia) and the synthesizing enzyme, ST8SIA2
C Sato, M Hane - Glycoconjugate journal, 2018 - Springer
Mental disorders, such as schizophrenia, bipolar disorder, and autism spectrum disorder,
are challenging to manage, worldwide. Understanding the molecular mechanisms …
are challenging to manage, worldwide. Understanding the molecular mechanisms …
Positive selection on schizophrenia-associated ST8SIA2 gene in post-glacial Asia
A number of loci are associated with highly heritable schizophrenia and the prevalence of
this mental illness has had considerable negative fitness effects on human populations …
this mental illness has had considerable negative fitness effects on human populations …
Differential effect of disease-associated ST8SIA2 haplotype on cerebral white matter diffusion properties in schizophrenia and healthy controls
JM Fullerton, P Klauser, RK Lenroot, AD Shaw… - Translational …, 2018 - nature.com
Brain white matter abnormalities are evident in individuals with schizophrenia, and also their
first-degree relatives, suggesting that some alterations may relate to underlying genetic risk …
first-degree relatives, suggesting that some alterations may relate to underlying genetic risk …
Effects of genetic variants of ST8SIA2 and NCAM1 genes on seasonal mood changes and circadian preference in the general population
SY Yang, JH Baek, Y Cho, EY Cho, Y Choi… - Chronobiology …, 2018 - Taylor & Francis
ABSTRACT ST8SIA2 and NCAM1 are functionally related genes forming polysialic acid
(PSA)-neural cell adhesion molecule (NCAM) complex in suprachiasmatic nucleus (SCN) …
(PSA)-neural cell adhesion molecule (NCAM) complex in suprachiasmatic nucleus (SCN) …
Hot genes in schizophrenia: how clinical datasets could help to refine their role
S Porcelli, SJ Lee, C Han, AA Patkar, D Albani… - Journal of Molecular …, 2018 - Springer
We investigated the effect of a set of SNPs within 5 genes identified by GWASs as possible
risk genes for schizophrenia (SCZ) in two independent samples, comprising 176 SCZ …
risk genes for schizophrenia (SCZ) in two independent samples, comprising 176 SCZ …
[PDF][PDF] The role of the neural cell adhesion molecule-associated polysialic acid in synaptic plasticity in the medial prefrontal cortex of the mouse (Mus musculus)
H Varbanov - 2018 - opendata.uni-halle.de
Cell adhesion molecules (CAMs) are cell-surface molecules that play a major role in the
developing central nervous system (CNS). In particular, CAMs promote cell-to-cell adhesion …
developing central nervous system (CNS). In particular, CAMs promote cell-to-cell adhesion …