Measurement of proton chemical shift anisotropy in solid-state NMR spectroscopy
L Liang, G Hou, X Bao - Solid State Nuclear Magnetic Resonance, 2018 - Elsevier
Proton chemical shift anisotropy (CSA) is significantly important as it provides the
information of the dynamics and local environmental structure of the proton. The …
information of the dynamics and local environmental structure of the proton. The …
Characterization of pharmaceutical cocrystals and salts by dynamic nuclear polarization-enhanced solid-state NMR spectroscopy
Multicomponent solids such as cocrystals have emerged as a way to control and engineer
the stability, solubility, and manufacturability of solid active pharmaceutical ingredients …
the stability, solubility, and manufacturability of solid active pharmaceutical ingredients …
[HTML][HTML] Calcium is an essential cofactor for metal efflux by the ferroportin transporter family
CN Deshpande, TA Ruwe, A Shawki, V Xin… - Nature …, 2018 - nature.com
Ferroportin (Fpn)—the only known cellular iron exporter—transports dietary and recycled
iron into the blood plasma, and transfers iron across the placenta. Despite its central role in …
iron into the blood plasma, and transfers iron across the placenta. Despite its central role in …
[HTML][HTML] Allosteric site inhibitor disrupting auto-processing of malarial cysteine proteases
Falcipains are major haemoglobinases of Plasmodium falciparum required for parasite
growth and development. They consist of pro-and mature domains that interact via 'hot …
growth and development. They consist of pro-and mature domains that interact via 'hot …
Probing the conformation of an IgG1 monoclonal antibody in lyophilized solids using solid-state hydrogen–deuterium exchange with mass spectrometric analysis …
Therapeutic proteins are often formulated as lyophilized products to improve their stability
and prolong shelf life. The stability of proteins in the solid-state has been correlated with …
and prolong shelf life. The stability of proteins in the solid-state has been correlated with …
BEST and SOFAST experiments for resonance assignment of histidine and tyrosine side chains in 13C/15N labeled proteins
NE Christou, B Brutscher - Journal of Biomolecular NMR, 2018 - Springer
Aromatic amino-acid side chains are essential components for the structure and function of
proteins. We present herein a set of NMR experiments for time-efficient resonance …
proteins. We present herein a set of NMR experiments for time-efficient resonance …
Analysis of functional cross-protomer contacts in green proteorhodopsin oligomers by DNP-enhanced solid-state NMR
J Maciejko - 2018 - publikationen.ub.uni-frankfurt.de
The membrane protein Green Proteorhodopsin (GPR), found in an uncultured marine γ-
proteobacterium, is a retinal binding protein and contains a conserved structure of seven …
proteobacterium, is a retinal binding protein and contains a conserved structure of seven …
Structural aspects and chemical species involved in the hemeperoxidases catalytic oxidation of hydrogen sulfide by hydrogen peroxide and oxygen
BB Ríos González - 2018 - scholar.uprm.edu
Hydrogen sulfide (H2S) has gained attention since it is implied in human physiological
functions with potential therapeutically effects. Furthermore, H2S interacts with …
functions with potential therapeutically effects. Furthermore, H2S interacts with …
Sulfheme formation mechanism and spectra analysis using QM/MM and TDDFT
HD Arbelo López - 2018 - scholar.uprm.edu
Since the 1863 discovery of a new green hemoglobin derivative called “sulfhemoglobin”, the
nature of its characteristic 618 nm absorption band and formation mechanism has been the …
nature of its characteristic 618 nm absorption band and formation mechanism has been the …