Silk fibroin/hydroxyapatite composites for bone tissue engineering

M Farokhi, F Mottaghitalab, S Samani… - Biotechnology …, 2018 - Elsevier
Silk fibroin (SF) is a natural fibrous polymer with strong potential for many biomedical
applications. SF has attracted interest in the field of bone tissue engineering due to its …

Nanotechnology in orthopedics: a clinically oriented review

WR Smith, PW Hudson, BA Ponce… - BMC musculoskeletal …, 2018 - Springer
The utility of nanotechnology in medicine, specifically within the field of orthopedics, is a
topic of extensive research. Our review provides a unique comprehensive overview of the …

PLLA-PHB fiber membranes obtained by solvent-free electrospinning for short-time drug delivery

K Cao, Y Liu, AA Olkhov, V Siracusa… - Drug delivery and …, 2018 - Springer
Fibers of poly (L-lactic acid)(PLLA)/polyhydroxybutyrate (PHB) with different concentrations
of the drug dipyridamole (DPD) were prepared using solvent-free melt electrospinning to …

Silk fibroin nanoparticles dyeing indocyanine green for imaging-guided photo-thermal therapy of glioblastoma

HL Xu, DL ZhuGe, PP Chen, MQ Tong, MT Lin… - Drug Delivery, 2018 - Taylor & Francis
Silk was easily dyed in traditional textile industry because of its strong affinity to many
colorants. Herein, the biocompatible silk fibroin was firstly extracted from Bombyx mori …

Preparation of a codelivery system based on vancomycin/silk scaffold containing silk nanoparticle loaded VEGF

N Hassani Besheli, S Damoogh, B Zafar… - ACS Biomaterials …, 2018 - ACS Publications
One of the main challenges of using biomaterials for inducing bone regeneration is the
bacterial resistance before complete bone repair. Biomaterials with both antibacterial and …

Nanotechnology-enabled materials for hemostatic and anti-infection treatments in orthopedic surgery

H Sun, L Lv, Y Bai, H Yang, H Zhou, C Li… - International journal of …, 2018 - Taylor & Francis
The hemostatic and anti-infection treatments in the field of orthopedics are always the pivotal
yet challenging topics. In the first part of this review, synthesized or naturally derived …

Silk‐Based antimicrobial polymers as a new platform to design drug‐free materials to impede microbial infections

AR Franco, E Palma Kimmerling, C Silva… - Macromolecular …, 2018 - Wiley Online Library
Surgical site infections (SSI) represent a serious health problem that occur after invasive
surgery, thus new antimicrobial biomaterials able to prevent SSI are needed. Silks are …

Bioresorbable microspheres with surface‐loaded nanosilver and apatite as dual‐functional injectable cell carriers for bone regeneration

P Wei, Z Yuan, Q Cai, J Mao… - Macromolecular Rapid …, 2018 - Wiley Online Library
Bone defect repair, especially in terms of infection, remains a big challenge in clinical
therapy. To meet clinical requirements, the dual‐functional strategy including antibacterial …

Iontophoresis-stimulated silk fibroin films as a peptide delivery system for wound healing

CN Lemos, C Cubayachi, K Dias, JN Mendonca… - European Journal of …, 2018 - Elsevier
Silk fibroin (SF) films containing a peptide, neurotensin (NT), stimulated by iontophoresis
were developed aiming to modulate the inflammatory process and prevent the growth of …

Three-dimensional nanofibrous microenvironment designed for the regulation of mesenchymal stem cells

L Jin, X Zhang, Z Li, G Chen, J Li, Z Wang, Y Gao - Applied Nanoscience, 2018 - Springer
The three-dimensional functional nanofibrous microenvironment plays a key role in the
regulation of cellular growth, because it can mimic the natural extracellular matrix structure …