[HTML][HTML] Self-replication of circular DNA by a self-encoded DNA polymerase through rolling-circle replication and recombination

Y Sakatani, T Yomo, N Ichihashi - Scientific reports, 2018 - nature.com
A major challenge in constructing artificial cells is the establishment of a recursive genome
replication system coupled with gene expression from the genome itself. One of the simplest …

Is defining life pointless? Operational definitions at the frontiers of biology

L Bich, S Green - Synthese, 2018 - Springer
Despite numerous and increasing attempts to define what life is, there is no consensus on
necessary and sufficient conditions for life. Accordingly, some scholars have questioned the …

[HTML][HTML] Automated in vitro evolution of a translation-coupled RNA replication system in a droplet flow reactor

T Yoshiyama, T Ichii, T Yomo, N Ichihashi - Scientific Reports, 2018 - nature.com
Automation is a useful strategy to make laborious evolutionary experiments faster and
easier. To date, several types of continuous flow reactors have been developed for the …

Synthetic modelling of biological communication: a theoretical and operational framework for the investigation of minimal life and cognition

L Bich, R Frick - Complex Systems, 2018 - hal.science
This paper analyses conceptual and experimental work in synthetic biology on different
types of interactions considered as minimal examples or models of communication. It …

Oscillating population dynamics and evolution of host and parasitic RNAs in an artificial cell

N Ichihashi - Artificial Life Conference Proceedings, 2018 - direct.mit.edu
The in vitro reconstitution of complex biological behavior from simple components is
challenging in wet ALIFE. Here, we present the reconstitution of host-parasite oscillation …

[PDF][PDF] Adaptation, diversification, and increase in

水内良 - 2018 - ir.library.osaka-u.ac.jp
Reconstituting biological abilities from known molecules is a direct approach to understand
sufficient factors for biological phenomena. It also provides a novel biological system to …