Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials

KZ Vardakas, GL Voulgaris, A Maliaros… - The Lancet infectious …, 2018 - thelancet.com
Background The findings of randomised controlled trials (RCT), observational studies, and
meta-analyses vary regarding the effectiveness of prolonged β-lactam infusion. We aimed to …

[HTML][HTML] Pharmacokinetics–pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients

RP Veiga, JA Paiva - Critical Care, 2018 - Springer
Antimicrobials are among the most important and commonly prescribed drugs in the
management of critically ill patients and beta-lactams are the most common antibiotic class …

[HTML][HTML] Antibiotic selection in the treatment of acute invasive infections by Pseudomonas aeruginosa: Guidelines by the Spanish Society of Chemotherapy

J Mensa, J Barberán, A Soriano, P Llinares… - Revista Española de …, 2018 - ncbi.nlm.nih.gov
Pseudomonas aeruginosa is characterized by a notable intrinsic resistance to antibiotics,
mainly mediated by the expression of inducible chromosomic β-lactamases and the …

Prolonged infusion piperacillin-tazobactam decreases mortality and improves outcomes in severely ill patients: results of a systematic review and meta-analysis

NJ Rhodes, J Liu, JN O'Donnell, JM Dulhunty… - Critical care …, 2018 - journals.lww.com
Objective: Piperacillin-tazobactam is a commonly used antibiotic in critically ill patients;
however, controversy exists as to whether mortality in serious infections can be decreased …

Continuous infusion versus intermittent bolus of beta-lactams in critically ill patients with respiratory infections: a systematic review and meta-analysis

YR Lee, PD Miller, SK Alzghari, DD Blanco… - European Journal of …, 2018 - Springer
Background Critically ill patients display altered pharmacokinetics and pharmacodynamics
and are more likely to be infected with more resistant pathogens. Beta-lactam antibiotics …

The role of extended infusion β-lactams in the treatment of bloodstream infections in patients with liver cirrhosis

M Bartoletti, RE Lewis, M Giannella… - Expert review of anti …, 2018 - Taylor & Francis
ABSTRACT Introduction: Bloodstream infections (BSIs) in patients with liver cirrhosis are
associated with significant morbidity and mortality. Early appropriated antibiotic treatment is …

[HTML][HTML] Обзор рекомендаций Испанского общества по химиотерапии по лечению острых инвазивных инфекций, вызванных Pseudomonas aeruginosa

АВ Дехнич, БЗ Белоцерковский… - Клиническая …, 2018 - cyberleninka.ru
Ввиду исключительной способности P. aeruginosa формировать устойчивость
практически ко всем доступным антибактериальным препаратам, выбор режима …

[图书][B] Clinical impact of colonization and infection by multidrug-resistant pseudomonas aeruginosa in the critically Ill patient

B Borgatta - 2018 - ddd.uab.cat
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