Role of copper in the onset of Alzheimer's disease compared to other metals
Alzheimer's disease (AD) is a neurodegenerative disorder that is characterized by amyloid
plaques in patients' brain tissue. The plaques are mainly made of β-amyloid peptides and …
plaques in patients' brain tissue. The plaques are mainly made of β-amyloid peptides and …
Peptides, peptidomimetics, and carbohydrate–peptide conjugates as amyloidogenic aggregation inhibitors for Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder accounting for 60–
80% of dementia cases. For many years, AD causality was attributed to amyloid-β (Aβ) …
80% of dementia cases. For many years, AD causality was attributed to amyloid-β (Aβ) …
Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex
LA Welikovitch, S Do Carmo, Z Maglóczky… - Acta …, 2018 - Springer
Growing evidence gathered from transgenic animal models of Alzheimer's disease (AD)
indicates that the intraneuronal accumulation of amyloid-β (Aβ) peptides is an early event in …
indicates that the intraneuronal accumulation of amyloid-β (Aβ) peptides is an early event in …
Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID
H Sasaguri, K Nagata, M Sekiguchi, R Fujioka… - Nature …, 2018 - nature.com
Abstract Base Editor (BE) and Target-AID (activation-induced cytidine deaminase) are
engineered genome-editing proteins composed of Cas9 and cytidine deaminases. These …
engineered genome-editing proteins composed of Cas9 and cytidine deaminases. These …
Intracellular amyloid beta expression leads to dysregulation of the mitogen-activated protein kinase and bone morphogenetic protein-2 signaling axis
E Cruz, S Kumar, L Yuan, J Arikkath, SK Batra - PloS one, 2018 - journals.plos.org
Alzheimer's disease (AD) is a neurodegenerative syndrome classically depicted by the
parenchymal accumulation of extracellular amyloid beta plaques. However, recent findings …
parenchymal accumulation of extracellular amyloid beta plaques. However, recent findings …
[HTML][HTML] Magnesium in Alzheimer's disease
D Chui, Z Chen, J Yu, H Zhang, W Wang, Y Song… - 2018 - europepmc.org
Alzheimer's disease (AD) is the most common form of dementia. It is characterized by a
progressive cognitive impairment clinically, and excessive deposits of aggregated amyloid-β …
progressive cognitive impairment clinically, and excessive deposits of aggregated amyloid-β …
Fighting the Cause of Alzheimer's and GNE Myopathy
Age is the common risk factor for both neurodegenerative and neuromuscular diseases.
Alzheimer disease (AD), a neurodegenerative disorder, causes dementia with age …
Alzheimer disease (AD), a neurodegenerative disorder, causes dementia with age …
Assessing Cognition In A Mouse Model Of Alzheimer's Disease
JB Mels - 2018 - search.proquest.com
A major challenge in behavioural testing of Alzheimer's disease (AD) mouse models is a low
degree of standardization and translatability of tasks to humans. Bussey-Saksida …
degree of standardization and translatability of tasks to humans. Bussey-Saksida …
Investigation of Monoaminergic Neurotransmitter Systems as a Method to Study Alzheimer's Disease-Related Neurodegeneration
C Gallardo - 2018 - search.proquest.com
Alzheimer's disease (AD) is the most common neurodegenerative disease and leading
cause of dementia currently afflicting 5.4 million people in the United States. Memory …
cause of dementia currently afflicting 5.4 million people in the United States. Memory …
[图书][B] Development of a novel probiotic and synbiotic formulation for the management of neurodegenerative and other diseases
S Westfall - 2018 - search.proquest.com
The gut microbiota is composed of an intricate network of thousands of bacterial species
living synergistically within the gastrointestinal tract (GIT). Humans have coevolved with …
living synergistically within the gastrointestinal tract (GIT). Humans have coevolved with …