Tissue damage and inflammation are important triggers for regeneration and fibrosis. Tissue
damage not only induces inflammation in general, it also determines the type and …

Anti–vascular endothelial growth factor (VEGF) therapy has failed to improve survival in
patients with breast cancer (BC). Potential mechanisms of resistance to anti-VEGF therapy …

Mahuang, a famous traditional Chinese medicine, is widely used for the treatment of
common cold and inflammatory diseases in China. We investigated the protective effects of …

Objective SSc is an autoimmune disease characterized by progressive fibrosis of the skin
and internal organs. IL-6 and related cytokines that signal through STAT3 have been …

Subretinal fibrosis has been recognized as a feature of an advanced stage of exudative age-
related macular degeneration (AMD) that leads to irreversible loss of vision. This study was …

Background: Pulmonary hypertension (PH) is a devastating and progressive disease
characterized by excessive proliferation of pulmonary artery smooth muscle cells (PASMCs) …

New Findings What is the central question of this study? When do alterations in pulmonary
mechanics occur following chronic low‐dose administration of bleomycin? What is the main …

Objective Systemic sclerosis (SS c; scleroderma) is a chronic disease that affects the skin
and various internal organs. Dermal fibrosis is a major component of this disease. The …

Long-term exposure to traffic-related pollutants can lead to a variety of respiratory diseases,
including inflammation, asthma, and lung cancer; however, the underlying biological …

The present invention relates to an anti-CSF-1R antibody and binding fragments thereof,
DNA encoding the same, host cells comprising said DNA and methods of expressing the …