Sex-related responses after traumatic brain injury: Considerations for preclinical modeling

CB Späni, DJ Braun, LJ Van Eldik - Frontiers in neuroendocrinology, 2018 - Elsevier
Traumatic brain injury (TBI) has historically been viewed as a primarily male problem, since
men are more likely to experience a TBI because of more frequent participation in activities …

Effects of female sex steroids administration on pathophysiologic mechanisms in traumatic brain injury

M Khaksari, Z Soltani, N Shahrokhi - Translational stroke research, 2018 - Springer
Secondary brain damage following initial brain damage in traumatic brain injury (TBI) is a
major cause of adverse outcomes. There are many gaps in TBI research and a lack of …

[HTML][HTML] Neuroprotective effects of gallic acid in a rat model of traumatic brain injury: behavioral, electrophysiological, and molecular studies

MA Mirshekar, A Sarkaki, Y Farbood… - Iranian Journal of …, 2018 - ncbi.nlm.nih.gov
Objective (s): Traumatic brain injury (TBI) is one of the main causes of intellectual and
cognitive disabilities. Clinically, it is essential to limit the development of cognitive …

Effects of pregabalin on brain edema, neurologic and histologic outcomes in experimental traumatic brain injury

MS Meymandi, Z Soltani, G Sepehri, S Amiresmaili… - Brain research …, 2018 - Elsevier
Brain edema and increased intracranial pressure (ICP) are among the main causes of
neurological disturbance and mortality following traumatic brain injury (TBI). Since …

Coenzyme Q10 influences on the levels of TNF-α and IL-10 and the ratio of Bax/Bcl2 in a menopausal rat model following lumbar spinal cord injury

S Hassanzadeh, SB Jameie, M Soleimani… - Journal of Molecular …, 2018 - Springer
The roles of the immune response and apoptosis as potential mediators of secondary
damage in spinal cord injury (SCI) are being investigated. Research is also being done to …

Progesterone attenuates airway remodeling and glucocorticoid resistance in a murine model of exposing to ozone

X Zhang, W Bao, X Fei, Y Zhang, G Zhang, X Zhou… - Molecular …, 2018 - Elsevier
Airway remodeling is a vital component of chronic obstructive pulmonary disease (COPD).
Despite the broad anti-inflammation effects of glucocorticoids, they exhibit relatively little …

Effects of progesterone on the neonatal brain following hypoxia-ischemia

RB Fabres, LA da Rosa, SK de Souza… - Metabolic Brain …, 2018 - Springer
Progesterone displays a strong potential for the treatment of neonatal hypoxic-ischemic
encephalopathy since it has been shown to be beneficial in the treatment of the central …

[HTML][HTML] Does inhibition of angiotensin function cause neuroprotection in diffuse traumatic brain injury?

M Khaksari, MA Rajizadeh, MA Bejeshk… - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
Objective (s): Neuroprotection is created following the inhibition of angiotensin II type 1
receptor (AT1R). Therefore, the purpose of this research was examining AT1R blockage by …

Does the administration of melatonin during post-traumatic brain injury affect cytokine levels?

F Dehghan, N Shahrokhi, M Khaksari, Z Soltani… - …, 2018 - Springer
Increased levels of inflammatory cytokines after traumatic brain injury (TBI) can lead to brain
edema and neuronal death. In this study, the effect of melatonin on pro-inflammatory (IL-1ß …

[HTML][HTML] Role of melatonin receptors in the effect of estrogen on brain edema, intracranial pressure and expression of aquaporin 4 after traumatic brain injury

N Shahrokhi, M Khaksari, G AsadiKaram… - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
Objective (s): Traumatic brain injury (TBI) is one of the most common causes of death and
disability in modern societies. The role of steroids and melatonin is recognized as a …