[HTML][HTML] Early-and late-onset Alzheimer disease: Are they the same entity?

P Tellechea, N Pujol, P Esteve-Belloch… - Neurología (English …, 2018 - Elsevier
Early-onset Alzheimer disease (EOAD), which presents in patients younger than 65 years,
has frequently been described as having different features from those of late-onset …

Machine learning-based individual assessment of cortical atrophy pattern in Alzheimer's disease spectrum: development of the classifier and longitudinal evaluation

JS Lee, C Kim, JH Shin, H Cho, D Shin, N Kim… - Scientific reports, 2018 - nature.com
To develop a new method for measuring Alzheimer's disease (AD)-specific similarity of
cortical atrophy patterns at the individual-level, we employed an individual-level machine …

Patterns of progressive atrophy vary with age in Alzheimer's disease patients

CM Fiford, GR Ridgway, DM Cash, M Modat… - Neurobiology of …, 2018 - Elsevier
Age is not only the greatest risk factor for Alzheimer's disease (AD) but also a key modifier of
disease presentation and progression. Here, we investigate how longitudinal atrophy …

Neuropsychiatric profile in early versus late onset Alzheimer's disease

MC Ferreira, MJ Abreu, C Machado… - American Journal of …, 2018 - journals.sagepub.com
Background: The aim of this study was to investigate the frequency and severity of
neuropsychiatric symptoms (NPS) in patients with early onset Alzheimer's disease (EAOD) …

Disease course varies according to age and symptom length in Alzheimer's disease

J Barnes, JW Bartlett, DA Wolk… - Journal of …, 2018 - content.iospress.com
Health-care professionals, patients, and families seek as much information as possible
about prognosis for patients with Alzheimer's disease (AD); however, we do not yet have a …

Similar pattern of atrophy in early‐and late‐onset Alzheimer's disease

C Eckerström, N Klasson, E Olsson… - Alzheimer's & …, 2018 - Wiley Online Library
Introduction Previous research on structural changes in early‐onset Alzheimer's disease
(EOAD) and late‐onset Alzheimer's disease (LOAD) have reported inconsistent findings …

[HTML][HTML] Enfermedad de Alzheimer de inicio precoz y de inicio tardío:¿ son la misma entidad?

P Tellechea, N Pujol, P Esteve-Belloch, B Echeveste… - Neurología, 2018 - Elsevier
La enfermedad de Alzheimer de inicio precoz (EAIP), definida como la que se manifiesta
antes de los 65 años de edad, muestra ciertas características diferentes de la enfermedad …

The impact of APOE ɛ4 in Alzheimer's Disease differs according to age

J Kim, S Park, H Yoo, H Jang, Y Kim… - Journal of …, 2018 - content.iospress.com
We evaluated how the impact of apolipoprotein E4 (APOE4) differs according to age in
Alzheimer's disease (AD) patients. We recruited 846 AD patients and 815 cognitively normal …

Sex-related reserve hypothesis in Alzheimer's disease: Changes in cortical thickness with a five-year longitudinal follow-up

J Lee, H Cho, S Jeon, HJ Kim, YJ Kim… - Journal of …, 2018 - content.iospress.com
Background: Sex effects on the progression of Alzheimer's disease (AD) have received less
attention than other demographic factors, including onset age and education. Objective: The …

Caractérisation par imagerie TEP 18F-FDG de la maladie d'Alzheimer à début précoce

M Vanhoutte - 2018 - theses.hal.science
La maladie d'Alzheimer (AD) est la principale cause de démence neurodégénérative,
caractérisée à 95% par des formes tardives (LOAD) qui présentent des troubles mnésiques …