Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by
motor symptoms such as rigidity, rest tremor, and bradykinesia. However, a growing body of …

Highlights•Apathy and impulsivity are common consequences of frontotemporal lobar
degeneration syndromes.•Common frontostriatal loops mediate different modes of apathy …

Serotonin is implicated in multiple executive functions including goal-directed learning,
cognitive flexibility, response inhibition and emotional regulation. These functions are …

Inhibitory control requires precise regulation of activity and connectivity within multiple brain
networks. Previous studies have typically evaluated age-related changes in regional activity …

The distribution of pathology in frontotemporal dementia is anatomically selective, to distinct
cortical regions and with differential neurodegeneration across the cortical layers. The …

Impulse control disorders (ICD) are common neuropsychiatric disorders that can arise in
Parkinson's disease (PD) patients after commencing dopamine replacement therapy …

Objective: This study aimed to systematically review the effects of currently prescribed
antiparkinson medication on cognition in patients with mild-to-moderate Parkinson's disease …

Dopaminergic medications improve the motor symptoms of Parkinson's disease (PD), but
their effect on response inhibition, a critical executive function, remains unclear. Previous …

The phenomenon of impulsivity in Parkinson's disease appears as an arduous side effect of
dopaminergic therapy with potentially detrimental consequences for the life of the patients …

The present behavioral study delineates the impact of Parkinson's disease (PD) and of
dopaminergic medication on action control over voluntary behavior. Previous studies …