Pimarane diterpenes: Natural source, stereochemical configuration, and biological activity

P Reveglia, A Cimmino, M Masi, P Nocera, N Berova… - Chirality, 2018 - Wiley Online Library
Plants and fungi are seemingly inexhaustible sources of interesting natural products with
remarkable structural and biological diversity. One of the most important groups is the …

[HTML][HTML] Zerumbone from Zingiber zerumbet (L.) smith: a potential prophylactic and therapeutic agent against the cariogenic bacterium Streptococcus mutans

T Moreira da Silva, CD Pinheiro… - … and alternative medicine, 2018 - Springer
Background Essential oil obtained from rhizomes of the Zingiber zerumbet (L.) Smith
(popularly known in Brazil as bitter ginger) is mainly constituted by the biomolecule …

Antimicrobial Activity of the Constituents of Dalbergia tonkinensis and Structural-Bioactive Highlights

NT Son, M Oda, N Hayashi… - Natural Product …, 2018 - journals.sagepub.com
The vulnerable plant Dalbergia tonkinensis Prain, is a rare species, native to Vietnam.
Phytochemical investigations and biological evaluations of this species are quite limited …

Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase

LA Chibli, TJ Schmidt, MC Nonato, FA Calil… - European journal of …, 2018 - Elsevier
The flavoenzyme dihydroorotate dehydrogenase (DHODH) catalyzes the fourth reaction of
the de novo pyrimidine biosynthetic pathway, which exerts vital functions in the cells …

[HTML][HTML] Solvent Extraction and Identification of Active Anticariogenic Metabolites in Piper cubeba L. through 1H-NMR-Based Metabolomics Approach

RNA Raja Mazlan, Y Rukayadi, M Maulidiani, IS Ismail - Molecules, 2018 - mdpi.com
The aim of this study was to determine the effects of different solvents for extraction, liquid–
liquid partition, and concentrations of extracts and fractions of Piper cubeba L. on …

Kaurenoic Acid and its Sodium Salt Derivative: Antibacterial Activity Against Porphyromonas Gingivalis and their Mechanism of Action

CHG Martins, F Abrão, TS Moraes, PF Oliveira… - Future …, 2018 - Taylor & Francis
Aim: To evaluate the antibacterial activity of 12 kaurane-type diterpenes against a panel of
bacteria that cause endodontic infection. Methods & materials: We conducted tests against …

[HTML][HTML] Diterpenes of the pimarane type isolated from Viguiera arenaria: Promising in vitro biological potential as therapeutic agents for endodontics

S Marangoni, TS Moraes, SH Utrera… - Journal of …, 2018 - academicjournals.org
Viguiera arenaria, family Asteraceae, is a plant that contains diterpenoids, which make this
species potentially applicable in endodontics. More specifically, V. arenaria contains …

Crystal Structure and Biological Activity of Matricaria Ester Isolated from Tripleurospermum Inodorum (L.) Sch. Bip.

YМ Suleimen, K Van Hecke, ZA Ibatayev… - Journal of Structural …, 2018 - Springer
CRYSTAL STRUCTURE AND BIOLOGICAL ACTIVITY OF MATRICARIA ESTER ISOLATED
FROM TRIPLEUROSPERMUM INODORUM (L.) Sch. Bip. Page 1 0022-4766/18/5904-0988 © …

Bactericidal Kinetics and Antibiofilm Efficacy of Pimarane-Type Diterpenes from Viguiera arenaria Against Cariogenic Bacteria

JH Ferreira, RM Garcia, F Abrão, YA Fernandez… - Pharmacognosy …, 2018 - phcogj.com
Background: Dental caries is an infectious disease related to biofilm formation. Among the
microorganisms presents in the oral microbiota, Streptococcus mutans can form biofilm on …

Solvent Extraction and Identification of Active Anticariogenic Metabolites in Piper cubeba L. through ¹H-NMR-Based Metabolomics Approach.

Y Rukayadi, M Maulidiani, IS Ismail - Molecules (Basel, Switzerland), 2018 - europepmc.org
The aim of this study was to determine the effects of different solvents for extraction, liquid–
liquid partition, and concentrations of extracts and fractions of Piper cubeba L. on …