Juvenile myelomonocytic leukemia (JMML) is a unique clonal hematopoietic disorder of
early childhood characterized by hyperactivation of the RAS signal transduction pathway …

Introduction: Juvenile myelomonocytic leukemia (JMML) is a clonal hematopoietic disorder
of infancy/early childhood, resulting from oncogenic mutations in genes involved in the Ras …

Juvenile myelomonocytic leukemia (JMML) is a rare myeloproliferative disorder of early
childhood characterized by expansion of clonal myelomonocytic cells and hyperactive …

Objective: This study aimed to define the status of juvenile myelomonocytic leukemia
(JMML) patients in Turkey in terms of time of diagnosis, clinical characteristics, mutational …

Abnormalities of molecules involved in signal transduction pathways are connected to
Chronic Lymphocytic Leukemia (CLL) pathogenesis and a critical role has been already …

The growing body of genetic data have not only altered the classification of myeloid
neoplasms, but are also impacting patient management. Genetically-defined disease …

The NRAS oncoprotein is highly mutated in melanoma. However, to date, no comprehensive
proteomic study has been reported for NRAS. Here, we utilized the endogenous epitope …

The chronic myeloid leukemias are a heterogeneous group of hematological neoplasms
resulting from mutation in either a myeloid progenitor or stem cell, leading to a purely …

The NRAS oncoprotein is highly mutated in melanoma. However, to date, no comprehensive
proteomic study has been reported for NRAS. Here, we utilized the endogenous epitope …

Vasculopathies are a varied group of disorders that affect the vascular tree resulting in
arterial stenosis or dilatation causing multi-organ ischaemia and significant cardiac and …