Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases

AE Kane, DA Sinclair - Circulation research, 2018 - Am Heart Assoc
The sirtuin family of nicotinamide adenine dinucleotide–dependent deacylases (SIRT1–7)
are thought to be responsible, in large part, for the cardiometabolic benefits of lean diets and …

Dietary polyphenols: Structures, bioavailability and protective effects against atherosclerosis

AB Santhakumar, M Battino… - Food and Chemical …, 2018 - Elsevier
Epidemiological studies have demonstrated that nutritional habits, like those based on high
consumption of fruits and vegetables, have been associated with a longer life expectancy …

[HTML][HTML] Mediterranean diet and nonalcoholic fatty liver disease

C Anania, FM Perla, F Olivero, L Pacifico… - World journal of …, 2018 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is emerging as the most common chronic liver
disease, and is characterized by a wide spectrum of fat-liver disorders that can result in …

Resveratrol: A miraculous natural compound for diseases treatment

M Koushki, N Amiri‐Dashatan, N Ahmadi… - Food Science & …, 2018 - Wiley Online Library
Abstract Resveratrol (3, 5, 4′‐trihydroxystilbene) is a nonflavonoid polyphenol that
naturally occurs as phytoalexin. It is produced by plant sources such as grapes, apples …

Medicinal plants and bioactive natural compounds in the treatment of non-alcoholic fatty liver disease: A clinical review

M Bagherniya, V Nobili, CN Blesso… - Pharmacological …, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver diseases, and is closely
related to metabolic syndrome and its related conditions, diabetes mellitus and dyslipidemia …

The effects of resveratrol on markers of oxidative stress in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled clinical trial

SS Seyyedebrahimi, H Khodabandehloo… - Acta …, 2018 - Springer
Aims Oxidative stress plays a pivotal role in the pathogenesis of type 2 diabetes (T2D). In
vitro and animal studies have shown that resveratrol exerts an antioxidant effect, but clinical …

Effect of resveratrol supplementation on inflammatory markers: a systematic review and meta-analysis of randomized controlled trials

M Koushki, NA Dashatan, R Meshkani - Clinical therapeutics, 2018 - Elsevier
Purpose The evidence has suggested that resveratrol has anti-inflammatory effect; however,
the results are inconsistent and inconclusive. The aim of this study was to assess the effect …

Catalase and nonalcoholic fatty liver disease

SK Shin, HW Cho, SE Song, DK Song - Pflügers Archiv-European Journal …, 2018 - Springer
Obesity and insulin resistance are considered the main causes of nonalcoholic fatty liver
disease (NAFLD), and oxidative stress accelerates the progression of NAFLD. Free fatty …

Effects of resveratrol supplementation on liver fat content in overweight and insulin‐resistant subjects: A randomized, double‐blind, placebo‐controlled clinical trial

K Kantartzis, L Fritsche, M Bombrich… - Diabetes, Obesity …, 2018 - Wiley Online Library
We performed the largest randomized, placebo‐controlled clinical trial to date (N= 112, 12‐
week intervention) to investigate the effects and safety of resveratrol supplementation on …

[HTML][HTML] Resveratrol ameliorates maternal and post-weaning high-fat diet-induced nonalcoholic fatty liver disease via renin-angiotensin system

MM Tiao, YJ Lin, HR Yu, JM Sheen, IC Lin… - Lipids in health and …, 2018 - Springer
Background Nonalcoholic fatty liver disease (NAFLD) can develop in prenatal stages and
can be exacerbated by exposure to a postnatal high-fat (HF) diet. We investigated the …