The big five in fibrosis: Macrophages, myofibroblasts, matrix, mechanics, and miscommunication

P Pakshir, B Hinz - Matrix Biology, 2018 - Elsevier
Scarring is part of the normal healing response to tissue injury in all organs and required to
rapidly repair acute damages, mostly with extracellular matrix. A variety of different cells are …

Matrix metalloproteinases in emphysema

SA Gharib, AM Manicone, WC Parks - Matrix Biology, 2018 - Elsevier
Several studies have implicated a causative role for specific matrix metalloproteinases
(MMPs) in the development and progression of cigarette smoke-induced chronic obstructive …

Androgen and androgen receptor as enhancers of M2 macrophage polarization in allergic lung inflammation

M Becerra-Díaz, AB Strickland, A Keselman… - The Journal of …, 2018 - journals.aai.org
Allergic asthma is a disease initiated by a breach of the lung mucosal barrier and an
inappropriate Th2 inflammatory immune response that results in M2 polarization of alveolar …

The impaired proteases and anti-proteases balance in Idiopathic Pulmonary Fibrosis

A Menou, JW Duitman, B Crestani - Matrix Biology, 2018 - Elsevier
Abstract Idiopathic Pulmonary Fibrosis (IPF) is a devastating chronic, progressive and
irreversible disease that remains refractory to current therapies. Matrix metalloproteinases …

Matrix metalloproteinase-12 as an endogenous resolution promoting factor following myocardial infarction

AJ Mouton, OJR Gonzalez, AR Kaminski… - Pharmacological …, 2018 - Elsevier
Following myocardial infarction (MI), timely resolution of inflammation promotes wound
healing and scar formation while limiting excessive tissue damage. Resolution promoting …

Association of IL-13 rs20541 and rs1295686 variants with symptomatic asthma in a Saudi Arabian population

R Halwani, A Vazquez-Tello, R Kenana… - Journal of …, 2018 - Taylor & Francis
ABSTRACT Objective: Interleukin 13 (IL-13) plays a critical pro-inflammatory role in asthma.
Several single nucleotide polymorphisms (SNPs) are associated with asthma susceptibility …

4-1BB signaling promotes alveolar macrophages-mediated pro-fibrotic responses and crystalline silica-induced pulmonary fibrosis in mice

Y Lu, C Li, S Du, X Chen, X Zeng, F Liu… - Frontiers in …, 2018 - frontiersin.org
Silicosis is caused by exposure to crystalline silica (CS). We have previously shown that
blocking 4-1BB signaling attenuated CS-induced inflammation and pulmonary fibrosis …

Merkel cell polyomavirus and Langerhans cell neoplasm

I Murakami, N Wada, J Nakashima, M Iguchi… - Cell Communication and …, 2018 - Springer
Background The relationship between various external agents such as pollen, food, and
infectious agents and human sensitivity exists and is variable depending upon individual's …

Proteomic and transcriptomic analysis of lung tissue in OVA-challenged mice

Y Lee, YH Hwang, KJ Kim, AK Park, MJ Paik… - Archives of pharmacal …, 2018 - Springer
Asthma is a long term inflammatory disease of the airway of lungs characterized by variable
airflow obstruction and bronchospasm. Asthma is caused by a complex combination of …

[PDF][PDF] Изучение уровней интерлейкина-13 и альфа-1-дефензина у пациентов с хроническими диффузными заболеваниями печени

ВА Прищепенко, ГИ Юпатов… - Иммунопатология …, 2018 - immunopathology.com
Изучение уровней интерлейкина-13 и альфа-1-дефензина у пациентов с хрон Page 1
Иммунопатология, Аллергология, Инфектология 2018 N4 87 ИММУНОГЕПАТОЛОГИЯ …