Complementary and alternative treatments of multiple sclerosis: a review of the evidence from 2001 to 2016

SB Claflin, IAF van der Mei, BV Taylor - Journal of Neurology …, 2018 - jnnp.bmj.com
People with multiple sclerosis (PwMS) commonly use complementary and alternative
medicines (CAM), but an understanding of their efficacy is lacking. Here, we quantitatively …

[HTML][HTML] Metabolomic profiles for primary progressive multiple sclerosis stratification and disease course monitoring

D Stoessel, JP Stellmann, A Willing… - Frontiers in human …, 2018 - frontiersin.org
Primary progressive multiple sclerosis (PPMS) shows a highly variable disease progression
with poor prognosis and a characteristic accumulation of disabilities in patients. These …

Disease-modifying therapies for relapsing–remitting and primary progressive multiple sclerosis: a cost-utility analysis

M Zimmermann, E Brouwer, JA Tice, M Seidner… - CNS drugs, 2018 - Springer
Background Several disease-modifying therapies (DMTs) treat relapsing–remitting multiple
sclerosis (RRMS) and primary progressive multiple sclerosis (PPMS). Few comprehensive …

[HTML][HTML] A multiple treatment comparison of eleven disease-modifying drugs used for multiple sclerosis

V Hamidi, E Couto, T Ringerike… - Journal of clinical …, 2018 - ncbi.nlm.nih.gov
Background Several disease-modifying drug therapies are available for the treatment of
multiple sclerosis (MS). To ensure the most appropriate MS management, we assessed the …

[HTML][HTML] MD1003 (high-dose pharmaceutical-grade biotin) for the treatment of chronic visual loss related to optic neuritis in multiple sclerosis: a randomized, double …

A Tourbah, O Gout, A Vighetto, V Deburghgraeve… - CNS drugs, 2018 - Springer
Background Chronic visual loss is a disabling feature in patients with multiple sclerosis
(MS). It was recently shown that MD1003 (high-dose pharmaceutical-grade biotin or hdPB) …

Long-term disability trajectories in primary progressive MS patients: a latent class growth analysis

A Signori, G Izquierdo, A Lugaresi… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: Several natural history studies on primary progressive multiple sclerosis
(PPMS) patients detected a consistent heterogeneity in the rate of disability accumulation …

Ovarian aging is associated with gray matter volume and disability in women with MS

JS Graves, RG Henry, BAC Cree… - Neurology, 2018 - AAN Enterprises
Objective To determine if ovarian aging as measured by levels of anti-Müllerian hormone
(AMH) is associated with pattern of multiple sclerosis (MS) progression in women. Methods …

Brain atrophy and disability worsening in primary progressive multiple sclerosis: insights from the INFORMS study

DH Miller, FD Lublin, MP Sormani… - Annals of clinical …, 2018 - Wiley Online Library
Objective To investigate the relationship between brain volume and disability worsening
over≥ 3 years in the natural history of primary progressive multiple sclerosis using data from …

A contemporary profile of primary progressive multiple sclerosis participants from the NARCOMS Registry

A Salter, NP Thomas, T Tyry… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: Primary progressive multiple sclerosis (PPMS) represents 10%–15% of all
multiple sclerosis (MS) diagnoses. Information regarding socio-demographic and clinical …

Clinical presentation, course, and prognosis of multiple sclerosis in adults

M Olek, J Howard - UptoDate, 2018 - uptodate.com
Multiple sclerosis (MS) is the most common immune-mediated inflammatory demyelinating
disease of the central nervous system. The onset and phenotypes of MS will be reviewed …