Background Polyneuropathies (peripheral neuropathies) are the most common type of
disorder of the peripheral nervous system in adults, and specifically in the elderly, with an …

OBJECTIVE To study incident diabetic polyneuropathy (DPN) prospectively during the first
13 years after a screening-based diagnosis of type 2 diabetes and determine the associated …

Type 2 diabetes mellitus (T2D) is a disorder of glucose metabolism. It is a complex process
involving the regulation of insulin secretion, insulin sensitivity, gluconeogenesis, and …

Objectives: Diabetic peripheral neuropathy (DPN) is the most common and troublesome
complication of diabetes leading to great morbidity and resulting in a huge economic burden …

Mitochondrial trafficking plays a central role in dorsal root ganglion (DRG) neuronal cell
survival and neurotransmission by transporting mitochondria from the neuronal cell body …

Background Cardiac autonomic neuropathy (CAN) in diabetes is among the strongest risk
markers for future global and cardiovascular mortality. The aim of this study was to analyse …

OBJECTIVE To study cardiometabolic risk-factor trajectories (in terms of levels and changes
over time) preceding diabetic polyneuropathy (DPN) 13 years after a screen-detected …

Background Clinical and experimental studies in patients with type 1 and type 2 diabetes
have demonstrated changes in ion channel function and nerve structure. In this study, we …

Background The purpose of this study was to evaluate the participation of satellite glial cells
(SGC), microglia and astrocytes in a model of streptozotocin-induced diabetes initiated in …

A 62-year-old diabetologist diagnosed himself to have diabetes type-2, with an HbA1c of
9.5. Five months after lifestyle intervention and a multi-drug approach, HbA1c was 6.3 …