Liver sinusoidal endothelial cells (LSECs) line the low shear, sinusoidal capillary channels
of the liver and are the most abundant non-parenchymal hepatic cell population. LSECs do …

Background Pericytes are multipotent cells present in every vascularized tissue in the body.
Despite the fact that they are well-known for more than a century, pericytes are still …

The liver is the largest solid organ in the body and is critical for metabolic and immune
functions. However, little is known about the cells that make up the human liver and its …

Spatially resolved single-cell RNA sequencing (scRNAseq) is a powerful approach for
inferring connections between a cell's identity and its position in a tissue. We recently …

βCatenin in hepatocytes, under the control of Wnts, regulates pericentral gene expression.
It also contributes to liver regeneration (LR) after partial hepatectomy (PH) by regulating …

The vLAMPS is a human, biomimetic liver MPS, in which the ECM and cell seeding of the
intermediate layer prior to assembly, simplifies construction of the model and makes the …

Background & Aims Neutrophils and liver sinusoidal endothelial cells (LSECs) both
contribute to sterile inflammatory injury during ischemia/reperfusion (I/R), a well-known liver …

In vivo visualization of the human lymphatic system is limited by the mode of delivery of
tracing agents, depth of field and size of the area examined, and specificity of the cell …

Owing to its strategic location in the body along with performing over 500 daily functions,
liver health is indispensable to survival. Following any form of acute or chronic hepatic …