Clinical utility of circulating non-coding RNAs—an update

S Anfossi, A Babayan, K Pantel, GA Calin - Nature reviews Clinical …, 2018 - nature.com
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …

A guide to miRNAs in inflammation and innate immune responses

C Nejad, HJ Stunden, MP Gantier - The FEBS journal, 2018 - Wiley Online Library
The discovery of micro RNA s (miRNAs) in the early 1990's has revolutionized our thinking
of post‐transcriptional gene control. miRNAs are involved in the regulation of almost every …

Rheumatoid arthritis and miRNAs: a critical review through a functional view

MC Moran-Moguel, S Petarra-del Rio… - Journal of …, 2018 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic autoimmune disease with severe joint inflammation
and destruction associated with an inflammatory environment. The etiology behind RA …

Deregulation of microRNA expression in purified T and B lymphocytes from patients with primary Sjögren's syndrome

SF Wang-Renault, S Boudaoud, G Nocturne… - Annals of the …, 2018 - ard.bmj.com
Objective MicroRNAs (miRNAs) play an important role in the pathogenesis of autoimmune
diseases such as primary Sjögren's syndrome (pSS). This study is the first to investigate …

Circulating serum miR-223-3p and miR-16-5p as possible biomarkers of early rheumatoid arthritis

M Dunaeva, J Blom, R Thurlings… - Clinical & Experimental …, 2018 - academic.oup.com
Small non-coding RNAs have emerged as possible biomarkers for various diseases
including autoimmune diseases. A number of studies have demonstrated that the …

MiR‐146a levels in rheumatoid arthritis and their correlation with disease activity: a meta‐analysis

SC Bae, YH Lee - International journal of rheumatic diseases, 2018 - Wiley Online Library
Objective To evaluate the relationship between miR‐146a levels and rheumatoid arthritis
(RA), and the correlation with RA activity. Methods For the meta‐analysis, we searched the …

The potential therapeutic role of miR-223 in bovine endometritis by targeting the NLRP3 inflammasome

G Zhao, K Jiang, Y Yang, T Zhang, H Wu… - Frontiers in …, 2018 - frontiersin.org
Bovine endometritis affects milk production and reproductive performance in dairy cows and
causes serious economic loss. The underlying molecular mechanisms or signaling …

Novel anti-inflammatory target of geniposide: inhibiting Itgβ1/Ras-Erk1/2 signal pathway via the miRNA-124a in rheumatoid arthritis synovial fibroblasts

Y Wang, L Dai, H Wu, Z Zhang, W Wang, J Fu… - International …, 2018 - Elsevier
Geniposide (GE) is an active component isolated from the fruit of Gardenia jasminoides Ellis
that has anti-inflammatory and other pharmacological effects; however, the underlying …

Plasma microRNA profiles in patients with early rheumatoid arthritis responding to adalimumab plus methotrexate vs methotrexate alone: a placebo-controlled clinical …

J Sode, SB Krintel, AL Carlsen, ML Hetland… - The Journal of …, 2018 - jrheum.org
Objective. The aim was to identify plasma (ie, cell-free) microRNA (miRNA) predicting
antitumor necrosis and/or methotrexate (MTX) treatment response in patients enrolled in an …

Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound‐Guided Synovial Biopsies in Rheumatoid Arthritis

AM Mandelin, PJ Homan, AM Shaffer… - Arthritis & …, 2018 - Wiley Online Library
Objective Currently, there are no reliable biomarkers for predicting therapeutic response in
patients with rheumatoid arthritis (RA). The synovium may unlock critical information for …