Obesity is an epidemic disease characterized by chronic low-grade inflammation associated
with a dysfunctional fat mass. Adipose tissue is now considered an extremely active …

With their ever-growing prevalence, obesity and diabetes represent major health threats of
our society. Based on estimations by the World Health Organization, approximately 300 …

Leptin is an endogenous protein having 167 amino acids and is derived from adipocytes. It
has tertiary structure that resembles with that of the pro‐inflammatory cytokines family. The …

Introduction: In the human organism, a constant interplay exists between the stress system
[which includes the activity of the hypothalamic-pituitary-adrenal (HPA) axis] and the …

Leptin plays a critical role in the regulation of energy balance and metabolic homeostasis.
Impairment of leptin signaling is closely involved in the pathogenesis of obesity and …

Аннотация В статье представлены современные данные о коморбидности депрессии
и ожирения с точки зрения причинно-следственных связей, общих …

Human beings have an innate need to form caring social bonds and be loved by others.
Thwarting this basic human need should have negative health consequences. This article …

Abstract Purpose of Review The first goal of this review is to discuss the evidence linking
belonging threats to immune function and food intake. The second goal is to evaluate …

В монографии рассмотрены структура, функции и сигнальные системы ключевых
адипокинов–лептина, адипонектина, апелина, висфатина и резистина, а также …

Background Fasting plasma leptin levels reflect fat mass, but dynamic leptin responses to
secretagogues, and the influence of race/ethnicity, have not been well studied. Here, we …