Design, synthesis, in vitro and in silico evaluation of a new series of oxadiazole-based anticancer agents as potential Akt and FAK inhibitors
In the current work, new 1, 3, 4-oxadiazole derivatives were synthesized and investigated for
their cytotoxic effects on A549 human lung adenocarcinoma, C6 rat glioma and NIH/3T3 …
their cytotoxic effects on A549 human lung adenocarcinoma, C6 rat glioma and NIH/3T3 …
Design, synthesis, and evaluation of a new series of thiazole-based anticancer agents as potent Akt inhibitors
In an attempt to develop potent anticancer agents targeting Akt, new thiazole derivatives (1–
10) were synthesized and investigated for their cytotoxic effects on A549 human lung …
10) were synthesized and investigated for their cytotoxic effects on A549 human lung …
Synthesis of new thiazolyl-pyrazoline derivatives and evaluation of their antimicrobial, cytotoxic and genotoxic effects
B Sever, MD Altıntop, HK Gencer… - Letters in Drug …, 2018 - ingentaconnect.com
Background: Pyrazolines have played a pivotal role in antimicrobial and anticancer drug
discovery. Moreover, thiazoles have attracted a great deal of interest due to their crucial …
discovery. Moreover, thiazoles have attracted a great deal of interest due to their crucial …
Synthesis and evaluation of new benzoxazole derivatives as potential antiglioma agents
M ALTINTOP, G AKALIN ÇİFTÇİ… - … OF RESEARCH IN …, 2018 - avesis.ogu.edu.tr
Gliomas account for the majority of human brain tumors and the incidence of gliomas is
expected to rise in upcoming years and therefore extensive efforts have been devoted to the …
expected to rise in upcoming years and therefore extensive efforts have been devoted to the …
Synthesis and evaluation of a new series of arylidene indanones as potential anticancer agents
Background: Arylidene indanones have attracted a great deal of interest due to their
outstanding therapeutic applications. In particular, considerable research has pointed out …
outstanding therapeutic applications. In particular, considerable research has pointed out …
Synthesis and biological applications of some salicylaldehyde thiosemicarbazone Schiff bases
Purpose: To synthesize, characterize and study the antimicrobial activity of Schiff bases
derived with salicylaldehyde thiosemicarbazone scaffold. Method: Five new Schiff base …
derived with salicylaldehyde thiosemicarbazone scaffold. Method: Five new Schiff base …
SYNTHESIS, CHARACTERISATION AND ANTIMICROBIAL PROPERTIES OF SOME SEMICARBAZONES AND THIOSEMICARBAZONES.
HR Fatondji, S Kpoviessi, F Gbaguidi… - International …, 2018 - search.ebscohost.com
Semicarbazones and thiosemicarbazones are inhibitors of DNA replication. This activity,
which is explained by their chelating property of certain metal ions cofactors of enzymes …
which is explained by their chelating property of certain metal ions cofactors of enzymes …