Mitochondria are key cell organelles in that they are responsible for energy production and
control many processes from signalling to cell death. The function of the mitochondrial …

Decades of research indicate mitochondria from Alzheimer's disease (AD) patients differ
from those of non-AD individuals. Initial studies revealed structural differences, and …

Alzheimer's disease (AD) is the most common cause of dementia and a great
socioeconomic burden in the aging society. Compelling evidence demonstrates that …

Sitagliptin is a member of a class of drugs that inhibit dipeptidyl peptidase (DPP‐4). It
increases the levels of the active form of incretins such as GLP‐1 (glucagon‐like peptide‐1) …

Memory impairment by the Amyloid-β 25–35 (Aβ 25–35) peptide in animal models has
provided an understanding of the causes behind the similar deterioration that occurs in …

To generate energy efficiently, the cell is uniquely challenged to co-ordinate the abundance
of electron transport chain protein subunits expressed from both nuclear and mitochondrial …

Beta-amyloid peptide (Aβ) contributes significantly to neurodegeneration during the
development of Alzheimer's disease (AD). Many studies showed that Aβ can cause oxidative …

Bhavesh D. Kevadiya a, Brendan M. Ottemann a, Midhun Ben Thomas a, Insiya Mukadam b,
Saumya Nigam a, JoEllyn McMillan a, Santhi Gorantla a, Tatiana K. Bronich b, Benson …