The NLRP3 inflammasome in acute myocardial infarction
The heart is extremely sensitive to ischaemic injury. During an acute myocardial infarction
(AMI) event, the injury is initially caused by reduced blood supply to the tissues, which is …
(AMI) event, the injury is initially caused by reduced blood supply to the tissues, which is …
Inflammasome, pyroptosis, and cytokines in myocardial ischemia-reperfusion injury
Myocardial ischemia-reperfusion injury induces a sterile inflammatory response, leading to
further injury that contributes to the final infarct size. Locally released danger-associated …
further injury that contributes to the final infarct size. Locally released danger-associated …
Anti‐inflammatory therapies in myocardial infarction: failures, hopes and challenges
S Huang, NG Frangogiannis - British journal of pharmacology, 2018 - Wiley Online Library
In the infarcted heart, the damage‐associated molecular pattern proteins released by
necrotic cells trigger both myocardial and systemic inflammatory responses. Induction of …
necrotic cells trigger both myocardial and systemic inflammatory responses. Induction of …
Cardiovascular magnetic resonance in acute st-segment–elevation myocardial infarction: Recent advances, controversies, and future directions
Although mortality after ST-segment elevation myocardial infarction (MI) is on the decline,
the number of patients developing heart failure as a result of MI is on the rise. Apart from …
the number of patients developing heart failure as a result of MI is on the rise. Apart from …
Interleukin-1 blockade in cardiovascular diseases: a clinical update
LF Buckley, A Abbate - European heart journal, 2018 - academic.oup.com
Abstract Interleukin-1 (IL-1) is the prototypical pro-inflammatory cytokine. IL-1 was implicated
as a cardiodepressant factor in septic shock, and subsequent pre-clinical and clinical …
as a cardiodepressant factor in septic shock, and subsequent pre-clinical and clinical …
Cytosolic DNA sensing promotes macrophage transformation and governs myocardial ischemic injury
DJ Cao, GG Schiattarella, E Villalobos, N Jiang… - Circulation, 2018 - Am Heart Assoc
Background: Myocardium irreversibly injured by ischemic stress must be efficiently repaired
to maintain tissue integrity and contractile performance. Macrophages play critical roles in …
to maintain tissue integrity and contractile performance. Macrophages play critical roles in …
Цитокины в патогенезе и лечении заболеваний человека
АС Симбирцев - 2018 - elibrary.ru
В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …
процессов, защитных реакций организма и в патогенезе иммунопатологических …
[HTML][HTML] Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction
Emerging evidence indicates that angiopoietin-2 (Angpt2), a well-recognized vascular
destabilizing factor, is a biomarker of poor outcome in ischemic heart disease. However, its …
destabilizing factor, is a biomarker of poor outcome in ischemic heart disease. However, its …
Therapeutic use of stem cells for myocardial infarction
M Madigan, R Atoui - Bioengineering, 2018 - mdpi.com
Myocardial infarction is a leading cause of morbidity and mortality worldwide. Although
medical and surgical treatments can significantly improve patient outcomes, no treatment …
medical and surgical treatments can significantly improve patient outcomes, no treatment …
Prognostic significance of remote myocardium alterations assessed by quantitative noncontrast T1 mapping in ST-segment elevation myocardial infarction
SJ Reinstadler, T Stiermaier, J Liebetrau… - JACC: cardiovascular …, 2018 - jacc.org
Objectives: This study assessed the prognostic significance of remote zone native T1
alterations for the prediction of clinical events in a population with ST-segment elevation …
alterations for the prediction of clinical events in a population with ST-segment elevation …