Role of neurogenic inflammation in local communication in the visceral mucosa

LA Birder, FA Kullmann - Seminars in immunopathology, 2018 - Springer
Intense research has focused on the involvement of the nervous system in regard to cellular
mechanisms underlying neurogenic inflammation in the pelvic viscera. Evidence supports …

[HTML][HTML] Role of proNGF/p75 signaling in bladder dysfunction after spinal cord injury

JC Ryu, K Tooke, SE Malley, A Soulas… - The Journal of …, 2018 - Am Soc Clin Investig
Loss of bladder control is a challenging outcome facing patients with spinal cord injury (SCI).
We report that systemic blocking of pro–nerve growth factor (proNGF) signaling through p75 …

A MAPP Network study: Overexpression of tumor necrosis factor-α in mouse urothelium mimics interstitial cystitis

W Yang, TJ Searl, R Yaggie… - American Journal of …, 2018 - journals.physiology.org
Interstitial cystitis/bladder pain syndrome is a chronic bladder condition associated with pain
and voiding dysfunction that is often regarded as a neurogenic cystitis. Patient symptoms are …

[HTML][HTML] Expression and function of chemokines CXCL9-11 in micturition pathways in cyclophosphamide (CYP)-induced cystitis and somatic sensitivity in mice

M Guo, P Chang, E Hauke, BM Girard… - Frontiers in systems …, 2018 - frontiersin.org
Changes in urinary bladder function and somatic sensation may be mediated, in part, by
inflammatory changes in the urinary bladder including the expression of chemokines. Male …

Nerve growth factor‐dependent hyperexcitability of capsaicin‐sensitive bladder afferent neurones in mice with spinal cord injury

T Shimizu, T Majima, T Suzuki, N Shimizu… - Experimental …, 2018 - Wiley Online Library
New Findings What is the central question of this study? Nerve growth factor (NGF) is
reportedly a mediator inducing urinary bladder dysfunction. Is NGF directly involved in …

Dietary macronutrient content affects inflammatory and fibrotic factors in normal and obstructed bladders

TG Adedeji, EO Olapade-Olaopa - Life sciences, 2018 - Elsevier
Aims To investigate the effects of diets on factors and markers of inflammation and fibrosis in
unobstructed and obstructed bladders of male Wistar rats. Materials and methods Partial …

[HTML][HTML] Potential Mechanisms Underlying the Increased Excitability of the Bladder Afferent Pathways in Interstitial Cystitis/Bladder Pain Syndrome

DS Kim - Urogenital Tract Infection, 2018 - synapse.koreamed.org
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic debilitating disorder
associated with lower urinary tract symptoms, including frequency, urgency, and suprapubic …

[PDF][PDF] The impact of intravesical treatments for bladder pain syndrome on normal bladder function

K Smith, R Chess-Williams, C McDermott - Philosophy, 2018 - research.bond.edu.au
Interstitial cystitis/bladder pain syndrome (IC/BPS) is characterized by pelvic pain, urinary
frequency, urgency and nocturia with no evidence of bacteria or pathology. Treatment is …

Aşırı Aktif Mesane Hastalarında İdrar Nerve Growth Faktör Düzeyi Ve Semptomlarla İlişkisi

ES Pelit, EK Başok, Bİ Başok, A Yıldırım… - Harran Üniversitesi Tıp …, 2018 - dergipark.org.tr
Background: High levels of nerve growth factor in urine and bladder tissue is associated with
the pathologies of lower urinary tract such as bladder outlet obstruction, over aktive bladder …