Molecular fluorescence‐guided surgery of peritoneal carcinomatosis of colorectal origin: A narrative review

JEKR Hentzen, SJ de Jongh… - Journal of surgical …, 2018 - Wiley Online Library
Patients with peritoneal carcinomatosis (PC) from colorectal origin may undergo
cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) as a …

Influence of protein properties and protein modification on biodistribution and tumor uptake of anticancer antibodies, antibody derivatives, and non‐Ig scaffolds

FJ Warnders, MN Lub‐de Hooge… - Medicinal research …, 2018 - Wiley Online Library
Newly developed protein drugs that target tumor‐associated antigens are often modified in
order to increase their therapeutic effect, tumor exposure, and safety profile. During the …

Biomarker expression in rectal cancer tissue before and after neoadjuvant therapy

LSF Boogerd, MJM Van Der Valk… - OncoTargets and …, 2018 - Taylor & Francis
Purpose Intraoperative identification of rectal cancer (RC) can be challenging, especially
because of fibrosis after treatment with preoperative chemo-and radiotherapy (CRT). Tumor …

七甲川菁荧光染料在肝细胞癌移植模型活体成像中的应用

王勤周, 张成, 李丽, 谭邓旭, 张彩勤, 师长宏 - 实验动物与比较医学, 2018 - slarc.org.cn
目的探索七甲川菁近红外(NIR) 荧光染料MHI-148 在肝癌移植模型中的代谢特征,
明确其识别肝细胞癌(HCC) 细胞的特异性. 方法体外培养人HCC 细胞系Hep3B …

Flow cytometric quantitation of EpCAM‐positive extracellular vesicles by immunomagnetic separation and phospholipid staining method

M Takao, Y Nagai, M Ito, T Ohba - Genes to Cells, 2018 - Wiley Online Library
Extracellular vesicles (EV) have attracted attention as circulating biomarkers for many
diseases, particularly cancer. Conventional immunofluorescence staining has been used for …

The application of heptamethine cyanine dye in optical imaging of hepatocellular carcinoma transplantation model

W Qin-zhou, Z Cheng, LI Li, T Deng-xu… - Laboratory Animal and …, 2018 - slarc.org.cn
Objective To explore the metabolic characteristics of heptamethine cyanine near-infrared
(NIR) fluorescence dye MHI-148 in hepatocellular carcinoma (HCC) xenograft model …

Preclinical models and molecular biomarkers. Tools to improve treatment in endometrial carcinoma

T Fonnes - 2018 - bora.uib.no
Background: Endometrial carcinoma is the fourth most common cancer in European women,
and incidence is increasing. No major improvements in treatment or survival have been …

Preclinical molecular imaging to study the biodistribution of antibody derivatives in oncology

JF Warnders - 2018 - research.rug.nl
The successful use of antibodies for the treatment of cancer has spurred the interest in the
development of antibody derivatives, such as Bispecific T-cell engagers (BiTEs) and …

[PDF][PDF] Fluorescence-enhanced surgical navigation: towards tailored tumor detection

LSF Boogerd - Lancet, 2018 - scholarlypublications …
Background" Tumour-targeted fluorescence imaging has the potential to advance current
practice of oncological surgery by selectively highlighting malignant tissue during surgery …

[PDF][PDF] Safeguarding ovarian tissue autotransplantation in cancer patients

ITA Peters - 2018 - scholarlypublications …
Safeguarding ovarian tissue autotransplantation in cancer patients© ITA Peters, 2018,
Leiden, the Netherlands. All rights reserved. No parts of this thesis may be reproduced …