Piperlongumine (piplartine) as a lead compound for anticancer agents–Synthesis and properties of analogues: A mini-review
K Piska, A Gunia-Krzyżak, P Koczurkiewicz… - European journal of …, 2018 - Elsevier
Piperlongumine, also known as piplartine, is an amide alkaloid of Piper longum L.(long
piper), a medical plant known from Ayurvedic medicine. Although was discovered well over …
piper), a medical plant known from Ayurvedic medicine. Although was discovered well over …
Piperine as a potential anti-cancer agent: a review on preclinical studies
Recently many studies showed anticancer activities of piperine, a pungent alkaloid found in
black pepper and some other Piper species. We attempted to summarize acquired data that …
black pepper and some other Piper species. We attempted to summarize acquired data that …
[HTML][HTML] Hesperidin, piperine and bee venom synergistically potentiate the anticancer effect of tamoxifen against breast cancer cells
Despite advances in cancer treatment, breast cancer remains one of the main life
threatening diseases in women. Most anti-breast cancer drugs cause severe health …
threatening diseases in women. Most anti-breast cancer drugs cause severe health …
Multi-target cinnamic acids for oxidative stress and inflammation: Design, synthesis, biological evaluation and modeling studies
E Pontiki, D Hadjipavlou-Litina - Molecules, 2018 - mdpi.com
Inflammation is a complex phenomenon that results as a healing response of organisms to
different factors, exerting immune signaling, excessive free radical activity and tissue …
different factors, exerting immune signaling, excessive free radical activity and tissue …
Diet therapy for cancer prevention and treatment based on traditional Persian medicine
B Javadi - Nutrition and cancer, 2018 - Taylor & Francis
Cancer is the second leading cause of death with profound socio-economic consequences
worldwide. Growing evidence suggests the crucial role of diet on cancer prevention and …
worldwide. Growing evidence suggests the crucial role of diet on cancer prevention and …
Th1-biased immunomodulation and in vivo antitumor effect of a novel piperine analogue
J Santos, M Brito, R Ferreira, AP Moura… - International Journal of …, 2018 - mdpi.com
Natural products have an important role as prototypes in the synthesis of new anticancer
drugs. Piperine is an alkaloid amide with antitumor activity and significant toxicity. Then, the …
drugs. Piperine is an alkaloid amide with antitumor activity and significant toxicity. Then, the …
Antineoplastic actions of cinnamic acids and their dimers in breast cancer cells: a comparative study
M Hunke, W Martinez, A Kashyap, T Bokoskie… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Breast cancer is the second leading cause of cancer-related deaths in US,
which necessitates constant research for medications with minimal adverse effects. The aim …
which necessitates constant research for medications with minimal adverse effects. The aim …
[HTML][HTML] Piperlongumine potentiates the effects of gemcitabine in in vitro and in vivo human pancreatic cancer models
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers due to a late
diagnosis and poor response to available treatments. There is a need to identify …
diagnosis and poor response to available treatments. There is a need to identify …
Cytotoxic and antiproliferative activity of kanchnar guggulu, an Ayurvedic formulation
P Tomar, YN Dey, D Sharma, MM Wanjari… - Journal of Integrative …, 2018 - Elsevier
Objective Kanchnar guggulu is a compound Ayurvedic formulation used in clinical practice
for the treatment of benign and malignant tumors. The present study investigates its cytotoxic …
for the treatment of benign and malignant tumors. The present study investigates its cytotoxic …
Trypanosoma cruzi: analysis of two different strains after piplartine treatment
GAL Vieira, MTA Silva, LO Regasini… - Brazilian Journal of …, 2018 - SciELO Brasil
The hemoflagellate protozoan, Trypanosoma cruzi, mainly transmitted by triatomine insects
through blood transfusion or from mother-to-child, causes Chagas' disease. This is a serious …
through blood transfusion or from mother-to-child, causes Chagas' disease. This is a serious …