Anticancer and cardio-protective effects of liposomal doxorubicin in the treatment of breast cancer

YL Franco, TR Vaidya, S Ait-Oudhia - Breast Cancer: Targets and …, 2018 - Taylor & Francis
Breast cancer (BC) is a highly prevalent disease, accounting for the second highest number
of cancer-related mortalities worldwide. The anthracycline doxorubicin (DOX), isolated from …

Cardiac toxicity from breast cancer treatment: can we avoid this?

J Caron, A Nohria - Current oncology reports, 2018 - Springer
Abstract Purpose of Review Breast cancer therapies, such as anthracyclines, trastuzumab,
and chest irradiation, have well-established cardiotoxicities that lead to adverse outcomes …

[HTML][HTML] Phase I feasibility study for intrathecal administration of trastuzumab in patients with HER2 positive breast carcinomatous meningitis

C Bonneau, G Paintaud, O Trédan, C Dubot… - European Journal of …, 2018 - Elsevier
Purpose Leptomeningeal carcinomatosis (MC) is commonly associated with HER2-positive
breast cancer (HER2-BC), with a poor prognosis and no standardised treatment. We …

[HTML][HTML] Heterogeneous distribution of trastuzumab in HER2-positive xenografts and metastases: role of the tumor microenvironment

JHE Baker, AH Kyle, SA Reinsberg, F Moosvi… - Clinical & experimental …, 2018 - Springer
Most HER2-positive metastatic breast cancer patients continue to relapse. Incomplete
access to all target HER2-positive cells in metastases and tumor tissues is a potential …

Hormone receptors status: a strong determinant of the kinetics of brain metastases occurrence compared with HER2 status in breast cancer

A Darlix, G Griguolo, S Thezenas, E Kantelhardt… - Journal of Neuro …, 2018 - Springer
Breast cancer (BC) metastatic behavior varies according to the hormone receptors (HR) and
HER2 statuses. Indeed, patients with triple-negative (TN) and HER2+ tumors are at higher …

The clinical and biological significance of tyrosine kinases in gastric cancer

N Khetpal, S Ali, R Kumar, MU Rashid… - Role of Tyrosine Kinases …, 2018 - Springer
Gastric cancer (GC) is the leading cause of cancer-related mortality, and its deadly nature
can be secondary to its presentation in advanced stages. Unavailability of any gold-standard …

Assessment of survival and cardiotoxicity of adjuvant trastuzumab among HER2 breast cancer patients in an oncology centre in Malaysia

HH Hasbullah, A Bustamam, LM Tho… - Journal of Clinical and …, 2018 - ir.uitm.edu.my
Adjuvant trastuzumab has been used in human epidermal growth factor-2 (HER2) breast
cancer to improve survival but with concern of cardiotoxicity. Our study is the first to review …

[PDF][PDF] CARDIOTOXICIDAD INDUCIDA POR FÁRMACOS BIOLÓGICOS Trastuzumab y bevacizumab

MC Campos, L Carrasco - 2018 - 147.96.70.122
La terapia biológica consiste en el uso de organismos vivos, sustancias procedentes de
organismos vivos, o versiones de esas sustancias producidas en el laboratorio para el …

[PDF][PDF] Pre-clinical Assessment of the Co-operative Effects of Trastuzumab and Panobinostat in HER2 Over-expressing Breast Cancer

M Medon - 2018 - minerva-access.unimelb.edu.au
The introduction of Trastuzumab (Herceptin®)-based chemotherapy combinations into
standard clinical practice has revolutionized the treatment of human epidermal growth factor …

Behandlung von lokoregionären Rezidiven eines HER2-positiven Primärtumors an der Universitätsfrauenklinik Ulm und ihren Netzwerkkliniken

M Lipp - 2018 - oparu.uni-ulm.de
In der vorliegenden retrospektiven, deskriptiven Versorgungsanalyse wird die Therapie des
lokoregionären Rezidivs (LR)„human epidermal growth factor receptor 2 “(HER2)-positiver …