[HTML][HTML] Gold-based medicine: a paradigm shift in anti-cancer therapy?

CI Yeo, KK Ooi, ERT Tiekink - Molecules, 2018 - mdpi.com
A new era of metal-based drugs started in the 1960s, heralded by the discovery of potent
platinum-based complexes, commencing with cisplatin [(H3N) 2PtCl2], which are effective …

Health benefits of vanadium and its potential as an anticancer agent

DC Crans, L Yang, A Haase, X Yang - Met. Ions Life Sci, 2018 - degruyter.com
Vanadium compounds have been known to have beneficial therapeutic properties since the
turn of the century, but it was not until 1965 when it was discovered that those effects could …

Novel tacrine platinum (II) complexes display high anticancer activity via inhibition of telomerase activity, dysfunction of mitochondria, and activation of the p53 …

QP Qin, SL Wang, MX Tan, ZF Wang, DM Luo… - European Journal of …, 2018 - Elsevier
In this work, we designed and synthesized tacrine platinum (II) complexes [PtClL (DMSO)]⋅
CH 3 OH (Pt1),[PtClL (DMP)](Pt2),[PtClL (DPPTH)](Pt3),[PtClL (PTH)](Pt4),[PtClL …

[HTML][HTML] Золотосодержащие комплексные соединения-противоопухолевые свойства, мишени и механизмы действия

ДБ Корман, ЛА Островская, ВА Кузьмин - Вопросы онкологии, 2018 - cyberleninka.ru
Золотосодержащие комплексные соединения (ЗСК) проявляют противоопухолевую
активность in vivo на моделях ксенографтов опухолей человека и перевиваемых …

Group IVB metallocene polyesters containing camphoric acid and preliminary cancer cell activity

CE Carraher Jr, MR Roner, AG Campbell… - … Journal of Polymeric …, 2018 - Taylor & Francis
Polyesters were formed from the reaction of the salt of camphoric acid and Group IVB
metallocene dichlorides using the interfacial polycondenzation process. The polyesters …

Spectroscopic investigation, fluorescence quenching, in vitro antibacterial and cytotoxicity assay of Co (II) and Ni (II) complexes containing 4-((3-ethoxy-2-hydroxy …

V Gomathi, R Selvameena - Inorganica Chimica Acta, 2018 - Elsevier
Expedient synthesis of Co (II) and Ni (II) complexes contriving the general molecular formula
[M (L 1) 2 Cl 2] have been exemplified, where L 1= 4-((3-ethoxy-2-hydroxy benzylidene) …

Ruthenium‐Based Anticancer Compounds: Insights into Their Cellular Targeting and Mechanism of Action

A Matos, F Mendes, A Valente, T Morais… - Ruthenium …, 2018 - Wiley Online Library
The identification of the mode of action of a drug is mandatory for the development of
clinically effective chemotherapeutics. Ruthenium complexes hold potential as alternatives …

An experimental study of the pharmacokinetics of the antitumor drug Aurumacryl

LA Ostrovskaya, DB Korman, JP Burmiy, VA Kuzmin… - Biophysics, 2018 - Springer
The distribution of the antitumor drug aurumacryl (intraperitoneally injected at a dose of 100
mg/kg) in the bodies of animals with Lewis lung carcinoma was studied. The determination …

[HTML][HTML] Racemic vs. enantiopure inert Ti (IV) complex of a single diaminotetrakis (phenolato) ligand in anticancer activity toward human drug-sensitive and-resistant …

M Miller, EY Tshuva - RSC advances, 2018 - pubs.rsc.org
A tetrakis (phenolato) Ti (IV) complex was synthesized in racemic and optically pure form,
exhibiting high hydrolytic stability, and similar cytotoxicity for all stereochemical forms on HT …

[PDF][PDF] Экспериментальное изучение фармакокинетики противоопухолевого препарата аурумакрил

ЛА Островская, ДБ Корман, ЖП Бурмий, ВА Кузмин… - Биофизика, 2018 - csl.isc.irk.ru
Пpоведено изучение pаcпpеделения пpотивоопуxолевого пpепаpата ауpумакpила
(дозиpовка–100 мг/кг, внутpибpюшинно) в оpганизме животныx–опуxоленоcителей …