Thrombospondin-1 regulation of latent TGF-β activation: A therapeutic target for fibrotic disease
JE Murphy-Ullrich, MJ Suto - Matrix Biology, 2018 - Elsevier
Transforming growth factor-β (TGF-β) is a central player in fibrotic disease. Clinical trials with
global inhibitors of TGF-β have been disappointing, suggesting that a more targeted …
global inhibitors of TGF-β have been disappointing, suggesting that a more targeted …
Pharmacological therapy of abdominal aortic aneurysm: an update
Y Wang, Z Liu, J Ren, M Xiang - Current vascular …, 2018 - ingentaconnect.com
Background: Abdominal aortic aneurysm (AAA), a progressive segmental abdominal aortic
dilation, is associated with high mortality. AAA is characterized by inflammation, smooth …
dilation, is associated with high mortality. AAA is characterized by inflammation, smooth …
Role of thrombospondin-1 in mechanotransduction and development of thoracic aortic aneurysm in mouse and humans
Y Yamashiro, BQ Thang, SJ Shin, CA Lino… - Circulation …, 2018 - Am Heart Assoc
Rationale: Abnormal mechanosensing of smooth muscle cells (SMCs) resulting from the
defective elastin-contractile units has been suggested to drive the formation of thoracic aortic …
defective elastin-contractile units has been suggested to drive the formation of thoracic aortic …
[HTML][HTML] Thrombospondin-4 mediates cardiovascular remodelling in angiotensin II-induced hypertension
T Palao, L Medzikovic, C Rippe, S Wanga… - Cardiovascular …, 2018 - Elsevier
Abstract Thrombospondin 4 (TSP-4) expression is induced in the heart and vasculature
under pathological conditions, including myocardial infarction, myocardial pressure …
under pathological conditions, including myocardial infarction, myocardial pressure …
Anionic nanoliposomes reduced atherosclerosis progression in Low Density Lipoprotein Receptor (LDLR) deficient mice fed a high fat diet
SM Krishna, JV Moxon, RJ Jose, J Li… - Journal of cellular …, 2018 - Wiley Online Library
Atherosclerosis is a systemic disease characterized by the deposition of cholesterol and
inflammatory cells within the arterial wall. Removal of cholesterol from the vessel wall may …
inflammatory cells within the arterial wall. Removal of cholesterol from the vessel wall may …
A diet enriched with tree nuts reduces severity of atherosclerosis but not abdominal aneurysm in angiotensin II-infused apolipoprotein E deficient mice
Background and aims Diets enriched with tree nuts have been demonstrated to reduce the
risk of atherosclerosis-related cardiovascular events. Abdominal aortic aneurysm (AAA) …
risk of atherosclerosis-related cardiovascular events. Abdominal aortic aneurysm (AAA) …
[PDF][PDF] Original Research Article Anionic nanoliposomes reduced atherosclerosis progression in Low Density Lipoprotein
J Golledge - minerva-access.unimelb.edu.au
Atherosclerosis is a systemic disease characterized by the deposition of cholesterol and
inflammatory cells within the arterial wall. Removal of cholesterol from the vessel wall may …
inflammatory cells within the arterial wall. Removal of cholesterol from the vessel wall may …
Development of Novel Collagen-targeted Protein-based MRI Contrast Agent for Imaging of Chronic Liver and Heart Diseases
M Salarian - 2018 - scholarworks.gsu.edu
Chronic diseases and conditions such as liver and heart diseases are among the most
common, costly, and preventable of all health problems. As of 2012 in the US, about half of …
common, costly, and preventable of all health problems. As of 2012 in the US, about half of …