Microfluidic devices enable novel means of emulating neurodegenerative disease
pathophysiology in vitro. These organ‐on‐a‐chip systems can potentially reduce animal …

As they differentiate from neuroblasts, nascent neurons become highly polarized and
elongate. Neurons extend and elaborate fine and fragile cellular extensions that form circuits …

Theoretical and in vivo neuroscience research suggests that functional information transfer
within neuronal networks is influenced by circuit architecture. Due to the dynamic …

Understanding the mechanisms that govern nervous tissues function remains a challenge.
In vitro two-dimensional (2D) cell culture systems provide a simplistic platform to evaluate …

Microporous membranes support the growth of neurites into and through micro-channels,
providing a different type of neural growth platform to conventional dish cultures …

Directing neurons to form predetermined circuits with the intention of treating neurological
disorders and neurodegenerative diseases is a fundamental goal and current challenge in …

Regeneration of injured neurons in complicated three-dimensional (3D) microenvironments
is a key approach for treating neurodegenerative diseases. Microfluidics provides a versatile …

Here we present a designer's approach to building cellular neuronal networks based on a
biocompatible negative photoresist with embedded coaxial feedthroughs made of …

Surface functionalization is a widely adopted technique for surface modification which
allows researchers to customize surfaces to integrate with their research. Surface …

The neuron patterning method has been applied to cultured neuronal networks to achieve
better reproducibility and various experimental conditions in brain research. However, as …