Staphylococcus aureus is a notorious opportunistic pathogen causing a plethora of
diseases. Recent research established that once phagocytosed by neutrophils and …

Lipid metabolism is thought to play a key role in the pathogenicity of several intracellular
bacteria. Bacterial lipolytic enzymes hydrolyze lipids from the host cell to release free fatty …

Acid sphingomyelinase (ASM) is a key enzyme in sphingolipid metabolism that converts
sphingomyelin to ceramide, thereby modulating membrane structures and signal …

Antibiotic resistance has been demonstrated during the entire duration of antibiotic use even
before medical utilization. Increasing resistance within virtually all microbes continues to be …

Pulmonary infections of cystic fibrosis (CF) patients with Staphylococcus aureus (S. aureus)
occur very early in the disease. The molecular details that cause infection-susceptibility of …

Abstract Significance: Tuberculosis (TB), which is caused by Mycobacterium tuberculosis, is
one of the most important infections worldwide. The sphingomyelinase/ceramide system …

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the deadliest and most
important infectious diseases worldwide. The sphingomyelinase/ceramide system, which …

Methoden der Fluoreszenz-Lokalisationsmikroskopie (engl. single-molecule localization
microscopy, SMLM) ermöglichen es Moleküle zu quantifizieren und deren Verteilung zu …