Tumors are complex tissues composed of variable amounts of both non-cellular components
(matrix proteins) and a multitude of stromal cell types, which are under an active cross-talk …

Melanoma remains an important health concern, given the steady increase in incidence and
acquisition of resistance to systemic therapies. The receptor for advanced glycation end …

Background: The receptor for advanced glycation end products (RAGE) has a critical role in
the pathogenesis of inflammation. In healthy children, its basal expression on the peripheral …

Background Age-related macular degeneration (AMD) is the leading cause of blindness in
people aged 65 years and older in developed countries. The pathogenesis of AMD has …

Objectives: Type-2 diabetes mellitus (T2DM) is an endocrine disease having a significant
genetic component. Polymorphisms of many genes may affect hereditary vulnerability of the …

The receptor of advanced glycation end-products (RAGE), is a type I single-pass
transmembrane protein, member of the multi-ligand immunoglobulin superfamily molecule …

Ο διαλυτός υποδοχέας των τελικών προϊόντων μη ενζυμικής γλυκοζυλίωσης (sRAGE)
εκφράζεται ευρέως σε διάφορα όργανα, συμπεριλαμβανομένου του ανδρικού γεννητικού …

Glaucoma encompasses a heterogeneous group of neurodegenerative processes
associated with progressive damage to the resident neurons within the retina known as …

Altas concentrações de glicose podem ativar a sinalização celular TLR4/NF-κB,
desencadeando a produção de mediadores proinflamatórios. Nós investigamos se o …