Neuromodulation in the restoration of function after spinal cord injury

ND James, SB McMahon, EC Field-Fote… - The Lancet …, 2018 - thelancet.com
Neuromodulation, the use of electrical interfaces to alter neuronal activity, has been
successful as a treatment approach in several neurological disorders, including deep brain …

Spinal cord stimulation for treating chronic pain: reviewing preclinical and clinical data on paresthesia-free high-frequency therapy

K Chakravarthy, H Richter, PJ Christo… - … : Technology at the …, 2018 - Elsevier
Background Traditional spinal cord stimulation (SCS) requires that paresthesia overlaps
chronic painful areas. However, the new paradigm high-frequency SCS (HF-SCS) does not …

[HTML][HTML] An implantable peripheral nerve recording and stimulation system for experiments on freely moving animal subjects

B Lee, MK Koripalli, Y Jia, J Acosta, MSE Sendi… - Scientific reports, 2018 - nature.com
A new study with rat sciatic nerve model for peripheral nerve interfacing is presented using a
fully-implanted inductively-powered recording and stimulation system in a wirelessly …

Prospective, randomized, sham-control, double blind, crossover trial of subthreshold spinal cord stimulation at various kilohertz frequencies in subjects suffering from …

A Al-Kaisy, S Palmisani, D Pang, K Sanderson… - … : Technology at the …, 2018 - Elsevier
Introduction The increasing use of high frequency paresthesia-free spinal cord stimulation
has been associated with improved outcomes in the therapy of neuropathic pain. What is …

Innovations in spinal cord stimulation for pain

SF Lempka, PG Patil - Current opinion in biomedical engineering, 2018 - Elsevier
Spinal cord stimulation (SCS) is a neuromodulation therapy used to treat medically
refractory chronic pain. In SCS, an implanted pulse generator produces electrical signals …

[HTML][HTML] New therapy for refractory chronic mechanical low back pain—restorative neurostimulation to activate the lumbar multifidus: one year results of a prospective …

K Deckers, K De Smedt, B Mitchell, D Vivian… - … : Technology at the …, 2018 - Elsevier
Objectives The purpose of the international multicenter prospective single arm clinical trial
was to evaluate restorative neurostimulation eliciting episodic contraction of the lumbar …

Ultrasound-guided percutaneous peripheral nerve stimulation: neuromodulation of the sciatic nerve for postoperative analgesia following ambulatory foot surgery, a …

BM Ilfeld, RA Gabriel, ET Said, AM Monahan… - Regional Anesthesia & …, 2018 - rapm.bmj.com
Background and Objectives Percutaneous peripheral nerve stimulation (PNS) is an
analgesic modality involving the insertion of a lead through an introducing needle followed …

Retrospective case series on the treatment of painful diabetic peripheral neuropathy with dorsal root ganglion stimulation

S Eldabe, A Espinet, A Wahlstedt, P Kang… - … : Technology at the …, 2018 - Elsevier
Background The dorsal root ganglion (DRG) has been identified as an important neural
structure in the development and maintenance of chronic pain. We present a retrospective …

RNA-seq of spinal cord from nerve-injured rats after spinal cord stimulation

KE Stephens, Z Chen, E Sivanesan, SN Raja… - Molecular …, 2018 - journals.sagepub.com
Spinal cord stimulation has become an important modality in pain treatment especially for
neuropathic pain conditions refractory to pharmacotherapy. However, the molecular control …

[HTML][HTML] Neuroanatomy, dorsal root ganglion

N Ahimsadasan, V Reddy, KS MZ, A Kumar - 2018 - europepmc.org
Dorsal nerve roots carry sensory neural signals to the central nervous system (CNS) from
the peripheral nervous system (PNS). Anatomically, a dorsal root ganglion (DRG) emerges …